Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Tinnitus
ADR ID BADD_A04316
ADR Hierarchy
04      Ear and labyrinth disorders
04.04      Inner ear and VIIIth cranial nerve disorders
04.04.01      Inner ear signs and symptoms
04.04.01.002      Tinnitus
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.07      Auditory nerve disorders
17.04.07.004      Tinnitus
Description A disorder characterized by noise in the ears, such as ringing, buzzing, roaring or clicking. [CTCAE] A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions. [MeSH]
MedDRA Code 10043882
MeSH ID D014012
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Aggravated ringing in ears | Ear buzzing | Ear cracking | Ear crackling | Ear hissing | Ear noises | Ear ringing | Ear roaring | Noises in head | Objective tinnitus | Ringing in ears | Subjective tinnitus | Tinnitus | Tinnitus aggravated | Tinnitus, unspecified | Worsening of tinnitus | Pulsatile tinnitus | Ringing-Buzzing-Tinnitus | Ringing Buzzing Tinnitus | Tinnitus, Tensor Palatini Induced | Tensor Palatini Induced Tinnitus | Tinnitus, Tensor Tympani Induced | Tensor Tympani Induced Tinnitus | Pulsatile Tinnitus | Tinnitus, Pulsatile | Tinnitus, Spontaneous Oto-Acoustic Emission | Tinnitus, Spontaneous Oto Acoustic Emission | Spontaneous Oto-Acoustic Emission Tinnitus | Spontaneous Oto Acoustic Emission Tinnitus | Tinnitus, Clicking | Clicking Tinnitus | Tinnitus, Leudet | Leudet Tinnitus | Tinnitus, Leudet's | Leudet's Tinnitus | Tinnitus, Leudets | Tinnitus, Noise Induced | Induced Tinnitus, Noise | Noise Induced Tinnitus | Tinnitus, Objective | Objective Tinnitus | Tinnitus, Subjective | Subjective Tinnitus | Tinnitus of Vascular Origin | Vascular Origin Tinnitus | Tinnitus, Vascular Origin
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02017Sibutramine hydrochloride--
BADD_D02018Sildenafil0.000999%
BADD_D02026Simvastatin0.000061%
BADD_D02028Sirolimus--
BADD_D02029Sitagliptin0.000260%
BADD_D02031Sitaxentan--
BADD_D02038Sodium ferric gluconate complex-
BADD_D02046Sodium nitroprusside--
BADD_D02047Sodium oxybate0.008557%
BADD_D02051Sodium thiosulfate--
BADD_D02053Sofosbuvir0.003387%
BADD_D02058Sorafenib--
BADD_D02062Sparfloxacin--
BADD_D02066Spironolactone0.000128%
BADD_D02071Streptomycin--
BADD_D02090Sulfadiazine--
BADD_D02091Sulfamethoxazole--
BADD_D02093Sulfasalazine--
BADD_D02097Sulindac--
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02103Suvorexant0.000889%
BADD_D02104Tacrine hydrochloride--
BADD_D02105Tacrolimus--
BADD_D02106Tadalafil0.003767%
BADD_D02108Tafluprost0.000419%
BADD_D02141Teichomycin--
BADD_D02143Telavancin--
BADD_D02147Telmisartan0.000260%
BADD_D02150Temozolomide--
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ADReCS-Target
ADR Term Drug Name Target