Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Spinal cord compression
ADR ID BADD_A04126
ADR Hierarchy
17      Nervous system disorders
17.10      Spinal cord and nerve root disorders
17.10.01      Spinal cord and nerve root disorders NEC
17.10.01.006      Spinal cord compression
Description A disorder characterized by pressure on the spinal cord. [CTCAE] Acute and chronic conditions characterized by external mechanical compression of the SPINAL CORD due to extramedullary neoplasm; EPIDURAL ABSCESS; SPINAL FRACTURES; bony deformities of the vertebral bodies; and other conditions. Clinical manifestations vary with the anatomic site of the lesion and may include localized pain, weakness, sensory loss, incontinence, and impotence. [MeSH]
MedDRA Code 10041549
MeSH ID D013117
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Spinal cord compression | Spinal cord compression NOS | Thoracic spinal cord compression | Spinal Cord Compression | Compression, Spinal Cord | Compressions, Spinal Cord | Spinal Cord Compressions | Myelopathy, Compressive | Compressive Myelopathy | Spinal Cord Compression, Extramedullary | Extramedullary Spinal Cord Compression | Conus Medullaris Syndrome | Conus Medullaris Syndromes | Syndrome, Conus Medullaris | Syndromes, Conus Medullaris
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01831Prednisolone0.000035%
BADD_D01834Prednisone0.000009%
BADD_D01835Pregabalin0.000078%
BADD_D01954Rivaroxaban--
BADD_D01971Rosuvastatin--
BADD_D01984Samarium--
BADD_D01985Samarium sm-153 lexidronam--
BADD_D01986Samarium sm-153 lexidronam pentasodium--
BADD_D02058Sorafenib0.000336%
BADD_D02100Sunitinib0.000280%
BADD_D02165Teriflunomide0.000241%
BADD_D02192Thalidomide0.000241%
BADD_D02297Triptorelin--
BADD_D02344Vemurafenib0.000112%
BADD_D02373Warfarin0.000112%
BADD_D02375Water--
BADD_D02392Zoledronic acid--
BADD_D02412Octreotide--
BADD_D02490Apalutamide0.000334%
BADD_D02586Radium ra-223 dichloride-
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