Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Small cell lung cancer
ADR ID BADD_A04083
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.19      Respiratory and mediastinal neoplasms malignant and unspecified
16.19.08      Respiratory tract small cell carcinomas
16.19.08.003      Small cell lung cancer
22      Respiratory, thoracic and mediastinal disorders
22.08      Respiratory tract neoplasms
22.08.01      Lower respiratory tract neoplasms
22.08.01.013      Small cell lung cancer
Description An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7) [MeSH]
MedDRA Code 10041067
MeSH ID D018288; D055752; D055752
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Oat cell carcinoma | Small cell carcinoma of the lung | Small cell lung cancer | Small cell lung cancer stage unspecified | Small cell lung cancer progression | Carcinoma, Small Cell | Carcinomas, Small Cell | Small Cell Carcinomas | Oat Cell Carcinoma | Small Cell Carcinoma | Carcinoma, Oat Cell | Carcinomas, Oat Cell | Oat Cell Carcinomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib0.000951%
BADD_D00284Bortezomib0.000112%
BADD_D00474Cisplatin0.000112%
BADD_D00511Clozapine0.005503%
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00775Enzalutamide0.000334%
BADD_D01008Gefitinib0.000448%
BADD_D01119Ibrutinib0.000112%
BADD_D01265Levetiracetam0.000079%
BADD_D01285Levothyroxine0.000005%
BADD_D01401Metformin0.000024%
BADD_D01629Osimertinib0.000951%
BADD_D01653Paclitaxel0.000168%
BADD_D01654Palbociclib0.000112%
BADD_D01783Pirfenidone0.000844%
BADD_D01835Pregabalin0.000052%
BADD_D01954Rivaroxaban0.000127%
BADD_D02105Tacrolimus0.000743%
BADD_D02236Tofacitinib0.000482%
BADD_D02248Topotecan0.000168%
BADD_D02364Vinorelbine tartrate--
BADD_D02392Zoledronic acid--
BADD_D02443Tiotropium0.000057%
BADD_D02464Fingolimod0.000362%
BADD_D02470Nintedanib0.000672%
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