Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Sleep paralysis
ADR ID BADD_A04076
ADR Hierarchy
17      Nervous system disorders
17.15      Sleep disturbances (incl subtypes)
17.15.02      Abnormal sleep-related events
17.15.02.005      Sleep paralysis
19      Psychiatric disorders
19.02      Sleep disorders and disturbances
19.02.02      Narcolepsy and associated conditions
19.02.02.004      Sleep paralysis
Description A common condition characterized by transient partial or total paralysis of skeletal muscles and areflexia that occurs upon awakening from sleep or less often while falling asleep. Stimuli such as touch or sound may terminate the episode, which usually has a duration of seconds to minutes. This condition may occur in normal subjects or be associated with NARCOLEPSY; CATAPLEXY; and hypnagogic HALLUCINATIONS. The pathophysiology of this condition is closely related to the normal hypotonia that occur during REM sleep. (From Adv Neurol 1995;67:245-271) [MeSH]
MedDRA Code 10041002
MeSH ID D020188
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Sleep paralysis | Sleep onset paralysis | Hypnopompic paralysis | Predormital paralysis | Postdormital paralysis | Hypnagogic paralysis | Sleep-wake transition paralysis | Sleep-wake transition speech loss | Sleep Paralysis | Paralysis, Sleep
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00277Bisoprolol0.000314%
BADD_D00312Bupropion0.000028%
BADD_D00480Clarithromycin0.000491%
BADD_D00504Clopidogrel0.000032%
BADD_D00720Doxepin--
BADD_D00932Fluoxetine0.000039%
BADD_D01102Hydroxybutanoic acid--
BADD_D01476Mirtazapine0.000592%
BADD_D01637Oxcarbazepine0.000375%
BADD_D02047Sodium oxybate0.006813%
BADD_D02103Suvorexant0.004639%
BADD_D02456Vilazodone0.004281%
BADD_D02491Valbenazine0.001830%
BADD_D02547Daridorexant-
BADD_D02563Lemborexant0.009525%
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