Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Skin wrinkling
ADR ID BADD_A04064
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.01      Cornification and dystrophic skin disorders
23.01.03      Skin dystrophies
23.01.03.001      Skin wrinkling
Description The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight. [MeSH]
MedDRA Code 10040954
MeSH ID D015595
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Skin wrinkling | Wrinkles | Wrinkling | Glabellar frown lines | Frown lines | Crow's feet | Nasolabial fold deepening | Nasolabial sulcus deepening | Nasolabial smile lines | Rhytides | Skin Aging | Aging, Skin | Solar Aging of Skin | Photoaging of Skin | Skin Wrinkling | Skin Wrinklings | Wrinkling, Skin
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00156Apremilast0.003279%
BADD_D00551Cyclosporine0.000376%
BADD_D00609Deoxycholic acid0.000603%
BADD_D00898Finasteride0.000175%
BADD_D01213Isotretinoin0.001750%
BADD_D01253Lenalidomide0.004750%
BADD_D01654Palbociclib0.000381%
BADD_D01709Penicillamine--
BADD_D01798Pomalidomide0.000530%
BADD_D01799Ponatinib0.000168%
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
BADD_D01933Ribavirin0.003956%
BADD_D02098Sumatriptan--
BADD_D02099Sumatriptan succinate--
BADD_D02223Tiopronin--
BADD_D02236Tofacitinib0.000820%
BADD_D02394Zolpidem--
BADD_D02395Zolpidem tartrate--
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