Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02407Upadacitinib0.001206%
BADD_D02418Doxylamine0.024146%
BADD_D02428Loperamide0.001014%
BADD_D02436Atorvastatin0.000155%
BADD_D02441Rasagiline0.002436%
BADD_D02442Magnesium oxide0.000182%
BADD_D02445Solifenacin0.000347%
BADD_D02463Pitavastatin0.002473%
BADD_D02471Oxygen0.002478%
BADD_D02472Sonidegib0.000168%
BADD_D02480Alectinib0.000448%
BADD_D02487Baricitinib0.000603%
BADD_D02504Lorlatinib0.000168%
BADD_D02505Gilteritinib0.000112%
BADD_D02509Brigatinib0.000280%
BADD_D02520Baloxavir marboxil0.001835%
BADD_D02566Lurbinectedin0.000112%
BADD_D02576Opicapone0.000367%
BADD_D02577Oseltamivir acid0.002603%
BADD_D02588Remdesivir0.000847%
BADD_D02594Selumetinib0.000168%
BADD_D02602Triheptanoin0.012937%
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ADReCS-Target
ADR Term Drug Name Target