Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Reye's syndrome
ADR ID BADD_A03876
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.07      Hepatocellular damage and hepatitis NEC
09.01.07.011      Reye's syndrome
11      Infections and infestations
11.07      Ancillary infectious topics
11.07.01      Inflammatory disorders following infection
11.07.01.004      Reye's syndrome
17      Nervous system disorders
17.13      Encephalopathies
17.13.01      Encephalopathies toxic and metabolic
17.13.01.002      Reye's syndrome
Description A form of encephalopathy with fatty infiltration of the LIVER, characterized by brain EDEMA and VOMITING that may rapidly progress to SEIZURES; COMA; and DEATH. It is caused by a generalized loss of mitochondrial function leading to disturbances in fatty acid and CARNITINE metabolism. [MeSH]
MedDRA Code 10039012
MeSH ID D012202
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Reye's syndrome | Reyes syndrome | Syndrome Reyes | Reye Syndrome | Reye-Johnson Syndrome | Reye Johnson Syndrome | Fatty Liver with Encephalopathy | Reye's Syndrome | Reye Syndrome, Adult | Adult Reye Syndrome | Reye's Syndrome, Adult | Adult Reye's Syndrome | Reye-Like Syndrome | Reye Like Syndrome | Reye's-Like Syndrome | Reye's Like Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00033Acetylsalicylic acid0.000077%
BADD_D00653Diclofenac0.000026%
BADD_D01120Ibuprofen--
BADD_D01243Lamotrigine0.000083%
BADD_D01397Mesalamine--
BADD_D01951Risperidone--
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