Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Renal rickets
ADR ID BADD_A03766
ADR Hierarchy
14      Metabolism and nutrition disorders
14.04      Bone, calcium, magnesium and phosphorus metabolism disorders
14.04.03      Phosphorus metabolism disorders
14.04.03.003      Renal rickets
15      Musculoskeletal and connective tissue disorders
15.02      Bone disorders (excl congenital and fractures)
15.02.03      Metabolic bone disorders
15.02.03.004      Renal rickets
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.01      Renal failure complications
20.01.01.003      Renal rickets
Description Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders. [MeSH]
MedDRA Code 10038519
MeSH ID D012080
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Renal rickets | Chronic Kidney Disease-Mineral and Bone Disorder | Chronic Kidney Disease Mineral and Bone Disorder | CKD-MBD | Renal Osteodystrophy | Osteodystrophies, Renal | Renal Osteodystrophies | Osteodystrophy, Renal | Renal Rickets | Rickets, Renal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01133Ifosfamide--
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