Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Renal failure
ADR ID BADD_A03749
ADR Hierarchy
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.005      Renal failure
Description Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. | A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. [MeSH]
MedDRA Code 10038435
MeSH ID D051437
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Failure kidney | Insufficiency renal | Kidney failure | Progressive renal failure | Renal failure | Renal failure aggravated | Renal failure following abortion and ectopic and molar pregnancies | Renal failure NOS | Renal failure unspecified | Renal failure, unspecified | Renal insufficiency | Renal insufficiency aggravated | Anuric renal failure | Renal Insufficiency | Renal Insufficiencies | Kidney Insufficiency | Insufficiency, Kidney | Kidney Insufficiencies | Kidney Failure | Failure, Kidney | Failures, Kidney | Kidney Failures | Renal Failure | Failure, Renal | Failures, Renal | Renal Failures
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02396Zonisamide--
BADD_D02412Octreotide--
BADD_D02421Foscarnet0.001552%
BADD_D02423Fondaparinux0.017269%
BADD_D02428Loperamide0.000338%
BADD_D02434Cinacalcet--
BADD_D02436Atorvastatin--
BADD_D02469Edoxaban0.000123%
BADD_D02470Nintedanib--
BADD_D02472Sonidegib0.000280%
BADD_D02473Sodium chloride--
BADD_D02475Methylene blue0.000183%
BADD_D02480Alectinib0.000839%
BADD_D02483Ribociclib0.001645%
BADD_D02487Baricitinib0.000844%
BADD_D02489Neratinib0.000336%
BADD_D02498Abemaciclib0.001052%
BADD_D02500Alpelisib0.000895%
BADD_D02502Letermovir0.000565%
BADD_D02506Erdafitinib0.000168%
BADD_D02509Brigatinib0.000336%
BADD_D02521Sodium zirconium cyclosilicate0.003346%
BADD_D02528Asciminib0.000112%
BADD_D02538Calcifediol0.005312%
BADD_D02539Calcium0.000979%
BADD_D02540Capmatinib0.000504%
BADD_D02548Darolutamide0.000334%
BADD_D02552Encorafenib0.000168%
BADD_D02553Entrectinib0.000112%
BADD_D02554Fedratinib0.000280%
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ADReCS-Target
ADR Term Drug Name Target