Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Osteogenesis imperfecta
ADR ID BADD_A03217
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.11      Musculoskeletal and connective tissue disorders congenital
15.11.01      Non-site specific bone disorders congenital
15.11.01.003      Osteogenesis imperfecta
03      Congenital, familial and genetic disorders
03.11      Musculoskeletal and connective tissue disorders congenital
03.11.01      Non-site specific bone disorders congenital
03.11.01.003      Osteogenesis imperfecta
Description COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I. [MeSH]
MedDRA Code 10031243
MeSH ID D010013
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Brittle bone disease | Osteogenesis imperfecta | Bruck syndrome | Osteogenesis Imperfecta | Brittle Bone Disease | Fragilitas Ossium | Ossiums, Fragilitas | Lobstein's Disease | Disease, Lobstein's | Lobsteins Disease | Osteogenesis Imperfecta, Type I | Osteogenesis Imperfecta with Blue Sclerae | Osteogenesis Imperfecta, Type 1 | Lobstein Disease | Disease, Lobstein | Osteogenesis Imperfecta Tarda | Osteogenesis Imperfecta Tardas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid--
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