Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Oesophageal achalasia
ADR ID BADD_A03135
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.03      Gastrointestinal dyskinetic disorders
07.02.03.004      Oesophageal achalasia
Description A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus). [MeSH]
MedDRA Code 10030136
MeSH ID D004931
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Achalasia | Achalasia cardiae | Achalasia esophageal | Oesophageal achalasia | Oesophagus achalasia of | Primary achalasia | Megaesophagus | Esophageal achalasia | Esophagus achalasia of | Achalasia oesophageal | Megaoesophagus | Esophageal Achalasia | Achalasias, Esophageal | Esophageal Achalasias | Cardiospasm | Cardiospasms | Achalasias | Achalasia, Esophageal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00850Etodolac--
BADD_D00996Galantamine0.001604%
BADD_D01136Imatinib0.000246%
BADD_D01245Lansoprazole--
BADD_D01318Lorazepam0.000062%
BADD_D01401Metformin0.000008%
BADD_D01418Methotrexate--
BADD_D01533Naproxen--
BADD_D01645Oxycodone0.000041%
BADD_D01654Palbociclib0.000246%
BADD_D01668Pantoprazole--
BADD_D01679Paroxetine--
BADD_D01682Paroxetine impurity a--
BADD_D01783Pirfenidone0.000241%
BADD_D01835Pregabalin--
BADD_D02105Tacrolimus0.002733%
BADD_D02266Trazodone--
BADD_D02379Zaleplon--
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