Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Nephrotic syndrome
ADR ID BADD_A03027
ADR Hierarchy
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.002      Nephrotic syndrome
Description A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH]
MedDRA Code 10029164
MeSH ID D009401; D009404
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02022Silvadene--
BADD_D02028Sirolimus--
BADD_D02033Sodium aurothiomalate--
BADD_D02053Sofosbuvir0.000282%
BADD_D02058Sorafenib0.000392%
BADD_D02071Streptomycin0.000060%
BADD_D02090Sulfadiazine--
BADD_D02091Sulfamethoxazole--
BADD_D02093Sulfasalazine0.000909%
BADD_D02097Sulindac--
BADD_D02100Sunitinib0.001007%
BADD_D02101Sunitinib malate--
BADD_D02105Tacrolimus0.003475%
BADD_D02154Tenofovir0.006786%
BADD_D02215Ticlopidine--
BADD_D02216Ticlopidine hydrochloride--
BADD_D02223Tiopronin0.000616%
BADD_D02257Trametinib0.000112%
BADD_D02264Trastuzumab--
BADD_D02287Trimethadione--
BADD_D02329Valproic acid0.000150%
BADD_D02367Voltaren--
BADD_D02369Voriconazole0.008713%
BADD_D02392Zoledronic acid0.002863%
BADD_D02452Icatibant-
BADD_D02470Nintedanib0.000828%
BADD_D02504Lorlatinib0.000168%
BADD_D02539Calcium0.000783%
The 5th Page    First    Pre   5    Total 5 Pages