Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hypertonia
ADR ID BADD_A02158
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.02      Muscle tone abnormal
17.05.02.001      Hypertonia
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.04      Muscle tone abnormalities
15.05.04.007      Hypertonia
Description Abnormal increase in skeletal or smooth muscle tone. Skeletal muscle hypertonicity may be associated with PYRAMIDAL TRACT lesions or BASAL GANGLIA DISEASES. [MeSH]
MedDRA Code 10020852
MeSH ID D009122
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Generally increased tone | Hypertonia | Hypertonicity | Hypertonus | Increased muscle tone | Muscular tone excessive | Muscular tone increased | Muscular tonus increased | Tone increased | Muscle hypertonia | Muscle Hypertonia | Hypertonia, Muscle | Hypertonias, Muscle | Muscle Hypertonias | Muscle Tone Increased | Increased, Muscle Tone | Tone Increased, Muscle | Muscular Hypertonicity | Hypertonicities, Muscular | Hypertonicity, Muscular | Muscular Hypertonicities | Hypermyotonia | Hypermyotonias | Hypertonia, Transient | Hypertonias, Transient | Transient Hypertonia | Transient Hypertonias | Hypertonia, Neonatal | Hypertonias, Neonatal | Neonatal Hypertonia | Neonatal Hypertonias | Hypertonia, Sphincter | Hypertonias, Sphincter | Sphincter Hypertonia | Sphincter Hypertonias | Hypertonia, Detrusor Muscle | Detrusor Muscle Hypertonia | Detrusor Muscle Hypertonias | Hypertonias, Detrusor Muscle | Muscle Hypertonia, Detrusor | Muscle Hypertonias, Detrusor | Hypertonia, Infantile | Hypertonias, Infantile | Infantile Hypertonia | Infantile Hypertonias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02210Tiagabine--
BADD_D02211Tiagabine hydrochloride--
BADD_D02230Tizanidine--
BADD_D02241Tolcapone--
BADD_D02247Topiramate0.000101%
BADD_D02254Tramadol0.000029%
BADD_D02255Tramadol hydrochloride--
BADD_D02281Trifluoperazine--
BADD_D02307Trovafloxacin--
BADD_D02308Trovafloxacin mesylate--
BADD_D02325Valdecoxib--
BADD_D02326Valganciclovir--
BADD_D02329Valproic acid0.001298%
BADD_D02335Vardenafil--
BADD_D02336Vardenafil hydrochloride--
BADD_D02337Varenicline--
BADD_D02346Venlafaxine0.000032%
BADD_D02347Venlafaxine hydrochloride--
BADD_D02355Vigabatrin0.000125%
BADD_D02367Voltaren--
BADD_D02369Voriconazole--
BADD_D02378Zalcitabine--
BADD_D02379Zaleplon--
BADD_D02384Zileuton--
BADD_D02389Ziprasidone hydrochloride--
BADD_D02390Ziprasidone hydrochloride monohydrate--
BADD_D02391Ziprasidone mesylate--
BADD_D02393Zolmitriptan--
BADD_D02394Zolpidem0.000038%
BADD_D02396Zonisamide--
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