Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Glucose-6-phosphate dehydrogenase deficiency
ADR ID BADD_A01862
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.08      Metabolic and nutritional disorders congenital
03.08.03      Inborn errors of carbohydrate metabolism (excl glucose)
03.08.03.001      Glucose-6-phosphate dehydrogenase deficiency
01      Blood and lymphatic system disorders
01.06      Haemolyses and related conditions
01.06.05      Red cell membrane and enzyme abnormalities
01.06.05.001      Glucose-6-phosphate dehydrogenase deficiency
14      Metabolism and nutrition disorders
14.14      Inborn errors of metabolism
14.14.03      Inborn errors of carbohydrate metabolism (excl glucose)
14.14.03.001      Glucose-6-phosphate dehydrogenase deficiency
Description A disease-producing enzyme deficiency subject to many variants, some of which cause a deficiency of GLUCOSE-6-PHOSPHATE DEHYDROGENASE activity in erythrocytes, leading to hemolytic anemia. [MeSH]
MedDRA Code 10018444
MeSH ID D005955; D005236
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Anaemia haemolytic G6PD | Anemia hemolytic G6PD deficiency | Favism | G-6 PD deficiency | Glucose-6-phosphate dehydrogenase deficienc | Glucose-6-phosphate dehydrogenase deficiency | Hemolytic anemia G6PD deficiency | Hemolytic anemia glucose-6-phos dehydrogenase deficiency | Hemolytic anemia glucose-6-phosphate dehydrogenase defici | Hemolytic anemia glucose-6-phosphate dehydrogenase deficienc | Anemia hemolytic G6PD | Haemolytic anaemia G6PD deficiency | Haemolytic anaemia glucose-6-phos dehydrogenase deficiency | Anaemia haemolytic G6PD deficiency | G6PD deficiency | Glucosephosphate Dehydrogenase Deficiency | Deficiencies, Glucosephosphate Dehydrogenase | Dehydrogenase Deficiencies, Glucosephosphate | Dehydrogenase Deficiency, Glucosephosphate | Deficiency, GPD | Deficiencies, GPD | GPD Deficiencies | G6PD Deficiency | Deficiencies, G6PD | Deficiency, G6PD | G6PD Deficiencies | Glucose 6 Phosphate Dehydrogenase Deficiency | Glucosephosphate Dehydrogenase Deficiencies | GPD Deficiency | Hemolytic Anemia Due to G6PD Deficiency | Deficiency of Glucose-6-Phosphate Dehydrogenase | Deficiency of Glucose 6 Phosphate Dehydrogenase | Deficiency, Glucosephosphate Dehydrogenase | Glucose-6-Phosphate Dehydrogenase Deficiency | Deficiencies, Glucose-6-Phosphate Dehydrogenase | Deficiency, Glucose-6-Phosphate Dehydrogenase | Dehydrogenase Deficiencies, Glucose-6-Phosphate | Dehydrogenase Deficiency, Glucose-6-Phosphate | Glucose-6-Phosphate Dehydrogenase Deficiencies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00504Clopidogrel--
BADD_D00544Cyclo-upup--
BADD_D00567Dabrafenib mesylate--
BADD_D00580Dapsone--
BADD_D01023Glimepiride--
BADD_D01337Mafenide--
BADD_D01369Mefloquine--
BADD_D01427Methylene blue cation--
BADD_D01521Nalidixic acid--
BADD_D01576Nitrofurantoin--
BADD_D01577Nitrofurantoin (macrocrystals)--
BADD_D01578Nitrofurantoin (monohydrate/macrocrystals)--
BADD_D01579Nitroglycerin--
BADD_D01587Norfloxacin--
BADD_D01745Phenazopyridine--
BADD_D01746Phenazopyridine hydrochloride--
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