Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Exophthalmos
ADR ID BADD_A01560
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.04      Structural change, deposit and degeneration of eye NEC
06.09.04.001      Exophthalmos
05      Endocrine disorders
05.02      Thyroid gland disorders
05.02.02      Thyroid hyperfunction disorders
05.02.02.002      Exophthalmos
Description Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye. [MeSH]
MedDRA Code 10015683
MeSH ID D005094
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bulging eyes | Constant exophthalmos | Exophthalmos | Exophthalmos NOS | Exophthalmos, unspecified | Intermittent exophthalmos | Other exophthalmic conditions | Proptosis | Pulsating exophthalmos | Proptoses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01304Lithium cation--
BADD_D01305Lithium hydroxide--
BADD_D01318Lorazepam0.000031%
BADD_D01322Losartan0.000015%
BADD_D01418Methotrexate0.000114%
BADD_D01431Methylphenidate0.000041%
BADD_D01433Methylprednisolone0.000032%
BADD_D01434Methylprednisolone acetate--
BADD_D01435Methylprednisolone hemisuccinate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01533Naproxen--
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01831Prednisolone0.000035%
BADD_D01832Prednisolone acetate--
BADD_D01833Prednisolone sodium phosphate--
BADD_D01834Prednisone0.000022%
BADD_D01835Pregabalin--
BADD_D01869Propylthiouracil--
BADD_D01951Risperidone0.000121%
BADD_D02010Sertraline--
BADD_D02011Sertraline hydrochloride--
BADD_D02099Sumatriptan succinate--
BADD_D02105Tacrolimus0.000297%
BADD_D02247Topiramate0.000075%
BADD_D02271Triamcinolone--
BADD_D02272Triamcinolone acetonide0.000027%
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