Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dyspepsia
ADR ID BADD_A01369
ADR Hierarchy
07      Gastrointestinal disorders
07.01      Gastrointestinal signs and symptoms
07.01.02      Dyspeptic signs and symptoms
07.01.02.001      Dyspepsia
Description A disorder characterized by an uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach, bloating, heartburn, nausea and vomiting. [CTCAE] Impaired digestion, especially after eating. [MeSH]
MedDRA Code 10013946
MeSH ID D004415; D006356
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acid dyspepsia | Acid indigestion | Difficult digestion | Digestion impaired | Distress epigastric | Dyspepsia | Dyspepsia aggravated | Dyspepsia and other specified disorders of function of stomach | Epigastric burning | Epigastric distress | Epigastric food-related pain | Flatulent dyspepsia | Heartburn | Heartburn aggravated | Heartburn-like dyspepsia | Increasing indigestion | Indigestion | Indigestion acid | Indigestion nervous | Pyrosis | Sour stomach | Stomach burning sensation of | Ulcer-like dyspepsia | Waterbrash | Dyspepsia-aggravated | Maldigestion | Functional dyspepsia | Non-ulcer dyspepsia | Chronic heartburn | Gastrooesophageal burning | Gastroesophageal burning | Dyspepsias | Indigestions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02378Zalcitabine--
BADD_D02379Zaleplon--
BADD_D02381Ziconotide--
BADD_D02383Zidovudine--
BADD_D02384Zileuton--
BADD_D02389Ziprasidone hydrochloride--
BADD_D02391Ziprasidone mesylate--
BADD_D02392Zoledronic acid--
BADD_D02393Zolmitriptan0.002031%
BADD_D02394Zolpidem--
BADD_D02395Zolpidem tartrate--
BADD_D02396Zonisamide--
BADD_D02397Zopiclone--
BADD_D02398Zuclopenthixol--
BADD_D02407Upadacitinib0.002652%
BADD_D02411Voxelotor-
BADD_D02412Octreotide0.000782%
BADD_D02428Loperamide--
BADD_D02434Cinacalcet0.032602%
BADD_D02436Atorvastatin--
BADD_D02445Solifenacin0.002344%
BADD_D02464Fingolimod--
BADD_D02468Cannabidiol0.002665%
BADD_D02470Nintedanib0.002205%
BADD_D02471Oxygen--
BADD_D02472Sonidegib0.000112%
BADD_D02483Ribociclib0.001343%
BADD_D02489Neratinib0.003873%
BADD_D02492Deflazacort0.000466%
BADD_D02495Duvelisib0.000302%
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