Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Unexplained chronic cough | Refractory chronic cough | Coughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02236Tofacitinib0.300209%
BADD_D02237Tofacitinib citrate--
BADD_D02241Tolcapone--
BADD_D02247Topiramate--
BADD_D02249Topotecan hydrochloride--
BADD_D02251Torsemide--
BADD_D02252Tositumomab--
BADD_D02253Trabectedin--
BADD_D02254Tramadol--
BADD_D02257Trametinib0.001724%
BADD_D02258Trametinib dimethyl sulfoxide--
BADD_D02259Trandolapril--
BADD_D02260Trandolaprilat--
BADD_D02264Trastuzumab--
BADD_D02265Travoprost--
BADD_D02266Trazodone--
BADD_D02268Treprostinil0.027075%
BADD_D02270Tretinoin--
BADD_D02271Triamcinolone--
BADD_D02272Triamcinolone acetonide--
BADD_D02281Trifluoperazine--
BADD_D02290Trimethoprim0.000787%
BADD_D02297Triptorelin--
BADD_D02298Triptorelin pamoate--
BADD_D02303Tropicamide0.002402%
BADD_D02307Trovafloxacin--
BADD_D02308Trovafloxacin mesylate--
BADD_D02314Umeclidinium0.001705%
BADD_D02315Umeclidinium bromide--
BADD_D02316Unoprostone--
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ADReCS-Target
ADR Term Drug Name Target