Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iloprost
Drug ID BADD_D01135
Description Iloprost is a synthetic analogue of prostacyclin PGI2 that dilates systemic and pulmonary arterial vascular beds. It is used to treat pulmonary arterial hypertension (PAH).
Indications and Usage Used for the treatment of pulmonary arterial hypertension.
Marketing Status approved; investigational
ATC Code B01AC11
DrugBank ID DB01088
KEGG ID D02721
MeSH ID D016285
PubChem ID 5311181
TTD Drug ID D05ZTH
NDC Product Code 66215-303; 40016-013; 82231-109; 54893-0017; 66215-302
UNII JED5K35YGL
Synonyms Iloprost | Ciloprost | ZK-36374 | ZK 36374 | ZK36374 | Ventavis
Chemical Information
Molecular Formula C22H32O4
CAS Registry Number 78919-13-8
SMILES CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.0010.000551%
Acute respiratory failure14.01.04.004; 22.02.06.0010.000164%-
Amnesia17.03.02.001; 19.20.01.0010.000206%
Angina pectoris02.02.02.002; 24.04.04.0020.000164%
Angina unstable02.02.02.004; 24.04.04.0040.000082%-
Arrhythmia02.03.02.0010.000493%-
Ascites02.05.04.002; 07.07.01.001; 09.01.05.0030.000493%
Asphyxia12.01.08.011; 22.02.02.0010.000329%-
Asthenia08.01.01.0010.001760%-
Atrial flutter02.03.03.0030.000082%
Back pain15.03.04.005--
Blindness unilateral06.02.10.007; 17.17.01.0160.000082%-
Blood pressure fluctuation24.06.01.0020.000123%-
Breast pain21.05.05.0030.000082%
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.0010.001809%
Cardiac failure02.05.01.0010.001974%
Cardiac failure congestive02.05.01.0020.000576%-
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.001110%-
Cardiomegaly02.04.02.0010.000164%-
Cardiovascular disorder02.11.01.010; 24.03.02.0090.000345%-
Cerebral haemorrhage17.08.01.003; 24.07.04.0010.000329%-
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.0020.000633%-
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.0030.001398%-
Choking22.12.03.0030.000329%-
Cholelithiasis09.03.01.0020.000247%-
Chronic obstructive pulmonary disease22.03.01.0070.000452%-
Circulatory collapse24.06.02.0010.000452%-
Colon cancer07.21.01.001; 16.13.01.0010.000082%-
Coma17.02.09.0010.000247%-
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