Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00553Cyproheptadine hydrochloride--
BADD_D00554Cyproterone--
BADD_D00555Cyproterone acetate--
BADD_D00556Cysteamine--
BADD_D00557Cysteamine bitartrate--
BADD_D00561Cytarabine hydrochloride--
BADD_D00564Dabigatran etexilate--
BADD_D00566Dabrafenib--
BADD_D00567Dabrafenib mesylate--
BADD_D00574Dalfampridine0.048182%
BADD_D00576Danazol--
BADD_D00577Dantrolene sodium--
BADD_D00578Dapagliflozin--
BADD_D00579Dapagliflozin propanediol--
BADD_D00581Daptomycin--
BADD_D00582Daratumumab--
BADD_D00584Darifenacin--
BADD_D00585Darifenacin hydrobromide--
BADD_D00586Darunavir--
BADD_D00589Dasatinib0.015368%
BADD_D00590Daunorubicin--
BADD_D00593Decitabine--
BADD_D00594Deferasirox0.058982%
BADD_D00599Degarelix--
BADD_D00600Degarelix acetate--
BADD_D00602Delamanid--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00612Desipramine--
BADD_D00613Desipramine hydrochloride--
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