Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Chronic lymphocytic leukaemia
ADR ID BADD_A00932
ADR Hierarchy
01      Blood and lymphatic system disorders
01.10      Leukaemias
01.10.06      Leukaemias chronic lymphocytic
01.10.06.001      Chronic lymphocytic leukaemia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.01      Leukaemias
16.01.06      Leukaemias chronic lymphocytic
16.01.06.001      Chronic lymphocytic leukaemia
Description A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease. [MeSH]
MedDRA Code 10008958
MeSH ID D015451
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic lymphatic leukaemia | Chronic lymphatic leukemia | Chronic lymphocytic leukaemia | Chronic lymphocytic leukaemia NOS | Chronic lymphocytic leukaemia variants | Chronic lymphocytic leukemia | Chronic lymphocytic leukemia variants | Chronic lymphoid leukaemia | Chronic lymphoid leukemia without mention of remission | CLL | CLL variants | Leukemia lymphocytic chronic | Lymphoid leukaemia, chronic | Lymphoid leukemia, chronic | Chronic lymphoid leukaemia without mention of remission | Leukaemia lymphocytic chronic | Chronic lymphoid leukemia | CLL progression | B-cell chronic lymphocytic leukaemia | B-cell chronic lymphocytic leukemia | Leukemia, Lymphocytic, Chronic, B-Cell | Leukemia, Lymphocytic, Chronic, B Cell | Lymphoma, Lymphocytic, Well-Differentiated | Lymphoma, Lymphoplasmacytoid, CLL | Lymphoma, Small Lymphocytic | Lymphocytic Lymphoma, Small | Lymphocytic Lymphomas, Small | Lymphomas, Small Lymphocytic | Small Lymphocytic Lymphoma | Small Lymphocytic Lymphomas | Lymphoma, Small Lymphocytic, Plasmacytoid | Lymphoma, Small-Cell | Lymphoma, Small Cell | Lymphomas, Small-Cell | Small-Cell Lymphomas | Lymphoplasmacytoid Lymphoma, CLL | CLL Lymphoplasmacytoid Lymphoma | CLL Lymphoplasmacytoid Lymphomas | Lymphoma, CLL Lymphoplasmacytoid | Lymphomas, CLL Lymphoplasmacytoid | Lymphoplasmacytoid Lymphomas, CLL | Small-Cell Lymphoma | Small Cell Lymphoma | Lymphoblastic Leukemia, Chronic | Chronic Lymphoblastic Leukemia | Chronic Lymphoblastic Leukemias | Leukemias, Chronic Lymphoblastic | Lymphoblastic Leukemias, Chronic | Lymphocytic Leukemia, Chronic | Lymphocytic Leukemia, Chronic, B Cell | Lymphocytic Leukemia, Chronic, B-Cell | Lymphocytic Lymphoma | Lymphocytic Lymphomas | Lymphomas, Lymphocytic | Lymphocytic Lymphoma, Diffuse, Well Differentiated | Lymphocytic Lymphoma, Diffuse, Well-Differentiated | Lymphocytic Lymphoma, Well Differentiated | Lymphocytic Lymphoma, Well-Differentiated | Lymphocytic Lymphomas, Well-Differentiated | Lymphoma, Well-Differentiated Lymphocytic | Lymphomas, Well-Differentiated Lymphocytic | Well-Differentiated Lymphocytic Lymphoma | Well-Differentiated Lymphocytic Lymphomas | Lymphoma, Lymphocytic | Lymphoma, Lymphocytic, Diffuse, Well Differentiated | B-Cell Chronic Lymphocytic Leukemia | B Cell Chronic Lymphocytic Leukemia | B-Cell Leukemia, Chronic | B Cell Leukemia, Chronic | B-Cell Leukemias, Chronic | Chronic B-Cell Leukemia | Chronic B-Cell Leukemias | Leukemia, Chronic B-Cell | Leukemias, Chronic B-Cell | B-Cell Malignancy, Low-Grade | B-Lymphocytic Leukemia, Chronic | B Lymphocytic Leukemia, Chronic | B-Lymphocytic Leukemias, Chronic | Chronic B-Lymphocytic Leukemia | Chronic B-Lymphocytic Leukemias | Leukemia, Chronic B-Lymphocytic | Leukemias, Chronic B-Lymphocytic | Chronic Lymphocytic Leukemia | Chronic Lymphocytic Leukemias | Lymphocytic Leukemias, Chronic | Diffuse Well-Differentiated Lymphocytic Lymphoma | Diffuse Well Differentiated Lymphocytic Lymphoma | Disrupted In B-Cell Malignancy | Leukemia, B Cell, Chronic | Leukemia, B-Cell, Chronic | Leukemia, Chronic Lymphatic | Leukemia, Chronic Lymphocytic | Leukemia, Chronic Lymphocytic, B-Cell | Leukemia, Lymphoblastic, Chronic | Leukemia, Lymphocytic, Chronic | Lymphoma, Lymphocytic, Diffuse, Well-Differentiated | Lymphoma, Lymphocytic, Well Differentiated
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00076Allopurinol--
BADD_D00194Azacitidine0.000112%
BADD_D00195Azathioprine0.000783%
BADD_D00230Bendamustine0.000582%
BADD_D00284Bortezomib0.000224%
BADD_D00286Bosutinib0.000246%
BADD_D00429Chlorambucil0.000168%
BADD_D00511Clozapine0.014674%
BADD_D00594Deferasirox0.001859%
BADD_D00680Dimethyl fumarate0.001600%
BADD_D00749Efavirenz0.003670%
BADD_D01023Glimepiride0.000064%
BADD_D01119Ibrutinib0.012984%
BADD_D01130Idelalisib0.001175%
BADD_D01136Imatinib0.000280%
BADD_D01250Lasofoxifene--
BADD_D01252Leflunomide0.000643%
BADD_D01253Lenalidomide0.006124%
BADD_D01322Losartan0.000010%
BADD_D01418Methotrexate--
BADD_D01549Nelarabine--
BADD_D01567Nilotinib0.000336%
BADD_D01629Osimertinib0.000112%
BADD_D01679Paroxetine--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01831Prednisolone0.000035%
BADD_D01913Ranitidine0.000100%
BADD_D01978Ruxolitinib0.000137%
BADD_D02344Vemurafenib0.000302%
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