Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Chronic hepatitis
ADR ID BADD_A00929
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.07      Hepatocellular damage and hepatitis NEC
09.01.07.021      Chronic hepatitis
11      Infections and infestations
11.07      Ancillary infectious topics
11.07.01      Inflammatory disorders following infection
11.07.01.009      Chronic hepatitis
Description INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors. | An aggressive form of chronic hepatitis involving extensive liver damage and cell injury beyond the portal tract. | A mild form of chronic hepatitis causing limited damage to the liver. [MeSH]
MedDRA Code 10008909
MeSH ID D006521
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic hepatitis | Chronic hepatitis, unspecified | Hepatitis chronic NOS | Other chronic hepatitis | Hepatitis, Chronic | Chronic Hepatitis | Cryptogenic Chronic Hepatitis | Chronic Hepatitis, Cryptogenic | Hepatitis, Cryptogenic Chronic | Hepatitis, Chronic, Cryptogenic | Hepatitis, Chronic Active | Chronic Active Hepatitis | Hepatitis, Chronic Persistent | Chronic Persistent Hepatitides | Chronic Persistent Hepatitis
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00142Anastrozole0.000477%
BADD_D00174Asfotase alfa--
BADD_D00195Azathioprine0.000313%
BADD_D00511Clozapine0.001223%
BADD_D00749Efavirenz0.003670%
BADD_D00858Everolimus--
BADD_D00981Gabapentin0.000021%
BADD_D01242Lamivudine--
BADD_D01401Metformin0.000005%
BADD_D01405Methadone--
BADD_D01418Methotrexate--
BADD_D01470Minocycline0.000649%
BADD_D01496Montelukast0.000015%
BADD_D01668Pantoprazole0.000033%
BADD_D01817Pramipexole0.000319%
BADD_D01834Prednisone0.000009%
BADD_D01954Rivaroxaban0.000063%
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