Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cerebellar ataxia
ADR ID BADD_A00836
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.02      Gait disturbances
08.01.02.006      Cerebellar ataxia
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.02      Coordination and balance disturbances
17.02.02.013      Cerebellar ataxia
Description Incoordination of voluntary movements that occur as a manifestation of CEREBELLAR DISEASES. Characteristic features include a tendency for limb movements to overshoot or undershoot a target (dysmetria), a tremor that occurs during attempted movements (intention TREMOR), impaired force and rhythm of diadochokinesis (rapidly alternating movements), and GAIT ATAXIA. (From Adams et al., Principles of Neurology, 6th ed, p90) [MeSH]
MedDRA Code 10008025
MeSH ID D002524
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Ataxia cerebellar | Cerebellar ataxia | Cerebellar ataxia in diseases classified elsewhere | Finger-nose ataxia | Other cerebellar ataxia | Acute cerebellar ataxia | Cerebellar Ataxia | Cerebellar Incoordination | Cerebellar Incoordinations | Incoordination, Cerebellar | Incoordinations, Cerebellar | Ataxia, Cerebellar | Ataxias, Cerebellar | Cerebellar Ataxias | Cerebellar Hemiataxia | Cerebellar Hemiataxias | Hemiataxia, Cerebellar | Hemiataxias, Cerebellar | Cerebellar Dysmetria | Cerebellar Dysmetrias | Dysmetria, Cerebellar | Dysmetrias, Cerebellar | Dysmetria | Dysmetrias | Hypermetria | Hypermetrias | Adiadochokinesis | Adiadochokineses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000029%
BADD_D00115Amiodarone--
BADD_D00349Capecitabine0.000224%
BADD_D00356Carbamazepine0.000186%
BADD_D00551Cyclosporine--
BADD_D00648Diazepam0.000176%
BADD_D00931Fluorouracil--
BADD_D01204Isoniazid0.002780%
BADD_D01265Levetiracetam0.000278%
BADD_D01449Metronidazole0.000564%
BADD_D01765Phenytoin0.001052%
BADD_D01905Raltegravir--
BADD_D01906Raltegravir potassium--
BADD_D02026Simvastatin0.000048%
BADD_D02105Tacrolimus0.000446%
BADD_D02247Topiramate0.000050%
BADD_D02464Fingolimod0.000603%
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