Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Carpal tunnel syndrome
ADR ID BADD_A00806
ADR Hierarchy
17      Nervous system disorders
17.09      Peripheral neuropathies
17.09.02      Mononeuropathies
17.09.02.001      Carpal tunnel syndrome
Description Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45) [MeSH]
MedDRA Code 10007697
MeSH ID D002349
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Carpal tunnel syndrome | Carpel tunnel syndrome | Syndrome carpel tunnel | Unilateral carpal tunnel syndrome | Carpal Tunnel Syndrome | Carpal Tunnel Syndromes | Syndrome, Carpal Tunnel | Syndromes, Carpal Tunnel | Amyotrophy, Thenar, Of Carpal Origin | Median Neuropathy, Carpal Tunnel | Compression Neuropathy, Carpal Tunnel | Entrapment Neuropathy, Carpal Tunnel
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01067Hex-hgrf--
BADD_D01086Hydrocortisone0.000046%
BADD_D01107Hydroxyprogesterone caproate-
BADD_D01119Ibrutinib0.000168%
BADD_D01162Insulin detemir--
BADD_D01167Interferon alfa-2b--
BADD_D01252Leflunomide0.000643%
BADD_D01253Lenalidomide0.005353%
BADD_D01257Letrozole0.000659%
BADD_D01260Leuprolide acetate--
BADD_D01285Levothyroxine0.000011%
BADD_D01300Lisinopril0.000012%
BADD_D01366Medroxyprogesterone acetate0.000119%
BADD_D01371Megestrol--
BADD_D01372Megestrol acetate--
BADD_D01375Meloxicam sodium--
BADD_D01378Memantine--
BADD_D01379Memantine hydrochloride--
BADD_D01401Metformin0.000014%
BADD_D01418Methotrexate0.000557%
BADD_D01449Metronidazole0.000026%
BADD_D01476Mirtazapine0.000120%
BADD_D01496Montelukast0.000032%
BADD_D01533Naproxen--
BADD_D01567Nilotinib0.000414%
BADD_D01654Palbociclib0.001097%
BADD_D01668Pantoprazole--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01834Prednisone0.000020%
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