Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Astrocytoma
ADR ID BADD_A00366
ADR Hierarchy
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.30      Nervous system neoplasms malignant and unspecified NEC
16.30.01      Nervous system neoplasms unspecified malignancy NEC
16.30.01.002      Astrocytoma
17      Nervous system disorders
17.20      Nervous system neoplasms malignant and unspecified NEC
17.20.01      Nervous system neoplasms unspecified malignancy NEC
17.20.01.002      Astrocytoma
Description Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) [MeSH]
MedDRA Code 10003571
MeSH ID D001254
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Astrocytoma | Astrocytomas | Astroglioma | Astrogliomas | Glioma, Astrocytic | Astrocytic Glioma | Astrocytic Gliomas | Gliomas, Astrocytic | Astrocytoma, Grade I | Astrocytomas, Grade I | Grade I Astrocytoma | Grade I Astrocytomas | Astrocytoma, Grade II | Astrocytomas, Grade II | Grade II Astrocytoma | Grade II Astrocytomas | Astrocytoma, Protoplasmic | Astrocytomas, Protoplasmic | Protoplasmic Astrocytoma | Protoplasmic Astrocytomas | Astrocytoma, Subependymal Giant Cell | Subependymal Giant Cell Astrocytoma | Pilocytic Astrocytoma | Astrocytoma, Pilocytic | Astrocytomas, Pilocytic | Pilocytic Astrocytomas | Childhood Cerebral Astrocytoma | Astrocytoma, Childhood Cerebral | Astrocytomas, Childhood Cerebral | Cerebral Astrocytoma, Childhood | Cerebral Astrocytomas, Childhood | Childhood Cerebral Astrocytomas | Fibrillary Astrocytoma | Astrocytoma, Fibrillary | Astrocytomas, Fibrillary | Fibrillary Astrocytomas | Gemistocytic Astrocytoma | Astrocytoma, Gemistocytic | Astrocytomas, Gemistocytic | Gemistocytic Astrocytomas | Intracranial Astrocytoma | Astrocytoma, Intracranial | Astrocytomas, Intracranial | Intracranial Astrocytomas | Juvenile Pilocytic Astrocytoma | Astrocytoma, Juvenile Pilocytic | Astrocytomas, Juvenile Pilocytic | Juvenile Pilocytic Astrocytomas | Pilocytic Astrocytoma, Juvenile | Pilocytic Astrocytomas, Juvenile | Oligoastrocytoma, Mixed | Mixed Oligoastrocytoma | Mixed Oligoastrocytomas | Oligoastrocytomas, Mixed | Anaplastic Astrocytoma | Anaplastic Astrocytomas | Astrocytoma, Anaplastic | Astrocytomas, Anaplastic | Astrocytoma, Grade III | Astrocytomas, Grade III | Grade III Astrocytoma | Grade III Astrocytomas | Cerebral Astrocytoma | Astrocytoma, Cerebral | Astrocytomas, Cerebral | Cerebral Astrocytomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00364Carboplatin0.000336%
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00566Dabrafenib0.000112%
BADD_D00680Dimethyl fumarate0.000600%
BADD_D01265Levetiracetam0.000119%
BADD_D02150Temozolomide--
BADD_D02257Trametinib0.000168%
BADD_D02355Vigabatrin0.000125%
BADD_D02526Larotrectinib0.000112%
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