Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Anal fissure
ADR ID BADD_A00206
ADR Hierarchy
07      Gastrointestinal disorders
07.03      Anal and rectal conditions NEC
07.03.01      Anal and rectal disorders NEC
07.03.01.002      Anal fissure
Description A disorder characterized by a tear in the lining of the anus. [CTCAE] A painful linear ulcer at the margin of the anus. It appears as a crack or slit in the mucous membrane of the anus and is very painful and difficult to heal. (Dorland, 27th ed & Stedman, 25th ed) [MeSH]
MedDRA Code 10002153
MeSH ID D005401
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Anal fissure | Fissure anal | Fissure in ano | Chronic anal fissure | Anal tear | Fissure in Ano | Anal Fissure | Fissure, Anal | Anal Ulcer | Anal Ulcers | Ulcer, Anal | Ulcers, Anal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01645Oxycodone--
BADD_D01668Pantoprazole--
BADD_D01831Prednisolone0.000087%
BADD_D01834Prednisone0.000013%
BADD_D01922Regorafenib0.000168%
BADD_D01933Ribavirin0.020570%
BADD_D02026Simvastatin0.000007%
BADD_D02058Sorafenib0.000224%
BADD_D02100Sunitinib0.000112%
BADD_D02142Telaprevir--
BADD_D02247Topiramate0.000075%
BADD_D02412Octreotide--
BADD_D02428Loperamide--
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