Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Akathisia
ADR ID BADD_A00129
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.02      Dyskinesias and movement disorders NEC
17.01.02.002      Akathisia
19      Psychiatric disorders
19.06      Anxiety disorders and symptoms
19.06.02      Anxiety symptoms
19.06.02.006      Akathisia
Description A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. [CTCAE] A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions. [MeSH]
MedDRA Code 10001540
MeSH ID D011595
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acathesia | Akathisia | Motor restlessness | Motor unrest compulsive | Akathisia aggravated | Acathisia | Psychomotor Agitation | Restlessness | Psychomotor Hyperactivity | Hyperactivity, Psychomotor | Psychomotor Restlessness | Restlessness, Psychomotor | Agitation, Psychomotor | Excitement, Psychomotor | Psychomotor Excitement
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02281Trifluoperazine--
BADD_D02282Trifluoperazine hydrochloride--
BADD_D02286Trimeprazine tartrate--
BADD_D02294Trimipramine--
BADD_D02329Valproic acid0.000369%
BADD_D02346Venlafaxine0.000097%
BADD_D02347Venlafaxine hydrochloride--
BADD_D02369Voriconazole--
BADD_D02371Vortioxetine0.002309%
BADD_D02389Ziprasidone hydrochloride--
BADD_D02390Ziprasidone hydrochloride monohydrate--
BADD_D02391Ziprasidone mesylate--
BADD_D02393Zolmitriptan--
BADD_D02394Zolpidem0.000051%
BADD_D02398Zuclopenthixol--
BADD_D02415Ziprasidone--
BADD_D02456Vilazodone0.000703%
BADD_D02488Esketamine0.000472%
BADD_D02491Valbenazine0.053996%
BADD_D02507Deutetrabenazine0.007322%
BADD_D02565Lumateperone0.001463%
BADD_D02638Thioproperazine--
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ADReCS-Target
ADR Term Drug Name Target