Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Akathisia
ADR ID BADD_A00129
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.02      Dyskinesias and movement disorders NEC
17.01.02.002      Akathisia
19      Psychiatric disorders
19.06      Anxiety disorders and symptoms
19.06.02      Anxiety symptoms
19.06.02.006      Akathisia
Description A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. [CTCAE] A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions. [MeSH]
MedDRA Code 10001540
MeSH ID D011595
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acathesia | Akathisia | Motor restlessness | Motor unrest compulsive | Akathisia aggravated | Acathisia | Psychomotor Agitation | Restlessness | Psychomotor Hyperactivity | Hyperactivity, Psychomotor | Psychomotor Restlessness | Restlessness, Psychomotor | Agitation, Psychomotor | Excitement, Psychomotor | Psychomotor Excitement
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01326Loxapine--
BADD_D01327Loxapine succinate--
BADD_D01330Lurasidone0.019380%
BADD_D01331Lurasidone hydrochloride--
BADD_D01350Maprotiline--
BADD_D01351Maprotiline hydrochloride--
BADD_D01373Melatonin0.000581%
BADD_D01431Methylphenidate0.000123%
BADD_D01442Metoclopramide0.022330%
BADD_D01443Metoclopramide hydrochloride--
BADD_D01476Mirtazapine0.000976%
BADD_D01487Molindone--
BADD_D01488Molindone hydrochloride--
BADD_D01508Mycophenolic acid--
BADD_D01510Nabilone--
BADD_D01599Olanzapine0.004315%
BADD_D01600Olanzapine pamoate--
BADD_D01617Ondansetron--
BADD_D01636Oxazepam0.002280%
BADD_D01643Oxybutynin--
BADD_D01656Paliperidone0.424529%
BADD_D01657Paliperidone palmitate--
BADD_D01679Paroxetine0.000086%
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01738Periciazine--
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ADReCS-Target
ADR Term Drug Name Target