Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Daprodustat
Drug ID BADD_D02546
Description Daprodustat has been used in trials studying the other, treatment, and basic science of Anaemia, Wound Healing, Tendon Injuries, Surgical Procedures, and Vascular Disease, Peripheral.
Indications and Usage Not Available
Marketing Status investigational
ATC Code B03XA07
DrugBank ID DB11682
KEGG ID D10874
MeSH ID C000599718
PubChem ID 91617630
TTD Drug ID D0F6JC
NDC Product Code 63379-107; 0173-0914; 63379-109; 0173-0897; 52482-020; 63379-110; 0173-0903; 0173-0911; 63379-108; 0173-0906; 63379-106
UNII JVR38ZM64B
Synonyms GSK1278863 | 2-(1,3-dicyclohexyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamido)acetic acid | daprodustat
Chemical Information
Molecular Formula C19H27N3O6
CAS Registry Number 960539-70-2
SMILES C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaemia01.03.02.0010.000198%
Cardiac failure02.05.01.0010.000297%
Cerebral infarction17.08.01.004; 24.04.06.0020.000297%-
Condition aggravated08.01.03.0040.000198%-
Death08.04.01.0010.000791%
Dysphagia07.01.06.0030.000435%
Hypothyroidism05.02.03.001; 14.11.01.0120.000198%
Marasmus14.03.02.0130.000395%-
Neoplasm malignant16.16.01.0010.000297%-
Renal impairment20.01.03.0100.000395%-
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