Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Hydrocortisone succinate
Drug ID BADD_D02523
Description Not Available
Indications and Usage Not Available
Marketing Status Not Available
ATC Code A01AC03; A07EA02; C05AA01; D07AA02; D07XA01; H02AB09; S01BA02; S01CB03; S02BA01
DrugBank ID DB14545
KEGG ID D01442
MeSH ID C007133
PubChem ID 16623
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms hydrocortisone hemisuccinate | cortisol-21-(hydrogen succinate) | cortisol hemisuccinate | cortisol succinate, sodium salt | hydrocortisone 21-sodium succinate | Sopolkort | hydrocortisone succinate | pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-, (11beta)- | hydrocortisone hemisuccinate anhydrous | cortisol succinate | Sopolcort H | A-hyrocort | Solu-Cortef
Chemical Information
Molecular Formula C25H34O8
CAS Registry Number 2203-97-6
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)COC(=O)CCC(=O)O)O)C)O
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Adrenal insufficiency05.01.02.001; 14.11.01.0040.005742%
Altered state of consciousness17.02.04.001; 19.07.01.0030.011483%Not Available
Anaphylactic reaction10.01.07.001; 24.06.03.0060.022967%
Anaphylactic shock10.01.07.002; 24.06.02.0040.020096%Not Available
Anxiety19.06.02.0020.005742%
Blood glucose increased13.02.02.0020.005742%Not Available
Blood pressure decreased13.14.03.0020.011483%Not Available
Bradycardia02.03.02.0020.008612%Not Available
Bronchospasm10.01.03.012; 22.03.01.0040.014354%
Cardiac arrest02.03.04.0010.001498%
Chest discomfort02.02.02.009; 08.01.08.019; 22.02.08.0010.011483%Not Available
Cough22.02.03.0010.005742%
Death08.04.01.001--
Diabetes insipidus05.03.03.004; 14.05.07.0030.008612%Not Available
Disseminated intravascular coagulation01.01.02.002; 24.01.01.0100.001498%
Drug hypersensitivity10.01.01.0010.025837%Not Available
Dyspnoea02.01.03.002; 22.02.01.0040.020096%
Dystonia17.01.03.0010.005742%Not Available
Erythema23.03.06.0010.014354%Not Available
Flushing08.01.03.025; 23.06.05.003; 24.03.01.0020.008612%
Headache17.14.01.0010.011483%
Hepatitis B09.01.09.003; 11.05.06.0020.005742%
Hypocalcaemia14.04.01.0040.005742%
Hypoglycaemia05.06.03.001; 14.06.03.0010.005742%
Hypokalaemia14.05.03.0020.008612%
Leukopenia01.02.02.0010.005742%Not Available
Malaise08.01.01.0030.005742%
Mania19.16.02.0020.017225%
Nausea07.01.07.0010.014354%
Nervousness19.06.02.0030.005742%Not Available
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