Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Carbon dioxide
Drug ID BADD_D02474
Description Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms. Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may be used in different situations, e.g. during bodily investigations, to inflate body cavities during surgery (such as key-hole surgery), iand in solid form (dry ice) for freezing of tissue and removal of warts.
Indications and Usage Carbon dioxide is commonly used as an insufflation gas for minimal invasive surgery (laparoscopy, endoscopy, and arthroscopy) to enlarge and stabilize body cavities to provide better visibility of the surgical area. It has been used also in cryotherapy and as respiratory stimulant before and after anesthesia. It could be used also in expansion of blood vessels if required, to increase carbon dioxide level after rapid breathing, and to stimulate breathing after a period of nonbreathing.
Marketing Status approved; investigational; vet_approved
ATC Code V03AN02
DrugBank ID DB09157
KEGG ID D00004
MeSH ID D002245
PubChem ID 280
TTD Drug ID Not Available
NDC Product Code 11054-130; 14961-008; 44076-021; 52438-014; 45149-014; 59578-125; 59788-003; 10297-020; 59579-003; 63961-010; 10014-005; 51486-005; 62045-7333; 10167-500; 48273-010; 21220-123; 34057-501; 49575-005; 53440-004; 55037-401; 10736-014; 17575-104; 11324-003; 82605-001; 11054-021; 42602-006; 12213-900; 46362-004
UNII 142M471B3J
Synonyms Carbon Dioxide | Dioxide, Carbon | Carbonic Anhydride | Anhydride, Carbonic
Chemical Information
Molecular Formula CO2
CAS Registry Number 124-38-9
SMILES C(=O)=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Air embolism12.02.05.008; 24.01.01.0010.010532%-
Cardiac arrest02.03.04.0010.001859%
Hypotension24.06.03.0020.001239%
Large intestine perforation07.04.06.005; 12.02.03.0050.001239%
Subcutaneous emphysema12.02.06.002; 23.07.04.0060.003965%
Pituitary haemorrhage05.03.04.005; 17.08.01.019; 24.07.04.0090.001239%-
Cerebral gas embolism17.08.01.071; 24.01.04.0200.001239%-
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