Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Velaglucerase alfa
Drug ID BADD_D02343
Description Velaglucerase alfa is a gene-activated human recombinant glucocerebrosidase used for the treatment of Type 1 Gaucher disease, caused by a deficiency of the lysosomal enzyme glucocerebrosidase. Additionally, Velaglucerase alfa has also been investigated for use in Type 3 Gaucher disease.
Indications and Usage Velaglucerase alfa is a hydrolytic lysosomal glucocerebroside-specific enzyme indicated for long-term enzyme replacement therapy for pediatric and adult patients with type 1 Gaucher disease.
Marketing Status approved; investigational
ATC Code A16AB10
DrugBank ID DB06720
KEGG ID D09029
MeSH ID Not Available
PubChem ID Not Available
TTD Drug ID D0G5ET
NDC Product Code 54092-701
UNII 23HYE36B0I
Synonyms Not Available
Chemical Information
Molecular Formula Not Available
CAS Registry Number 884604-91-5
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Activated partial thromboplastin time prolonged13.01.02.001--
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Back pain15.03.04.005--
Bone pain15.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Fatigue08.01.01.002--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Headache17.14.01.001--
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Nausea07.01.07.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Tachycardia02.03.02.007---
Upper respiratory tract infection11.01.13.009; 22.07.03.011--
Urticaria10.01.06.001; 23.04.02.001--
Infusion related reaction08.01.03.002; 10.01.01.017; 12.02.05.009--
Antibody test13.06.03.009---
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