Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vecuronium bromide
Drug ID BADD_D02341
Description Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.
Indications and Usage Vecuronium is a muscle relaxing agent and is used as an adjunct in general anesthesia.
Marketing Status approved; investigational
ATC Code M03AC03
DrugBank ID DB01339
KEGG ID D00767
MeSH ID D014673
PubChem ID 39764
TTD Drug ID D0Z8HG
NDC Product Code 68083-139; 0409-1632; 10695-021; 47335-932; 63323-782; 55150-235; 0143-9234; 51662-1475; 55486-1566; 67457-475; 55150-236; 67457-438; 53183-1308; 60870-0297; 63323-781; 60722-1008; 47335-931; 68083-140; 0703-2914; 51662-1547; 81565-206; 0143-9232
UNII 7E4PHP5N1D
Synonyms Vecuronium Bromide | Bromide, Vecuronium | Vecuronium Hydrobromide | Hydrobromide, Vecuronium | Norcuron | Vecuronium | Vecuronium Phosphate | Phosphate, Vecuronium | Vecuronium Citrate | Citrate, Vecuronium | Vecuronium Hydrochloride | Hydrochloride, Vecuronium | Vecuronium Maleate | Maleate, Vecuronium | NC-45 | NC 45 | NC45 | ORG-NC45 | ORG NC45 | ORG-NC 45 | ORG NC 45 | ORGNC 45 | ORG-NC-45 | ORGNC45 | Vecuronium Bromide, Quaternary Ion
Chemical Information
Molecular Formula C34H57BrN2O4
CAS Registry Number 50700-72-6
SMILES CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Apnoea22.02.01.001--
Bronchospasm10.01.03.012; 22.03.01.004--
Cardiac arrest02.03.04.0010.000057%
Death08.04.01.0010.000085%
Delayed recovery from anaesthesia12.02.20.005; 17.02.04.011---
Dermatitis23.03.04.002---
Drug ineffective08.06.01.0060.000433%-
Dyspnoea02.11.05.003; 22.02.01.0040.000125%
Erythema23.03.06.001---
Face oedema08.01.07.003; 10.01.05.002; 23.04.01.004--
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Immune system disorder10.02.01.001---
Injection site pain08.02.03.010; 12.07.03.011---
Injection site reaction08.02.03.014; 12.07.03.015--
Muscle atrophy15.05.03.003; 17.05.03.004---
Muscle twitching15.05.03.0050.000085%-
Muscular weakness15.05.06.001; 17.05.03.005--
Myopathy15.05.05.0010.000057%-
Nervous system disorder17.02.10.001---
Neuromuscular block prolonged12.02.20.008; 17.05.04.005---
Paralysis17.01.04.0040.000239%-
Rash23.03.13.001---
Rash erythematous23.03.13.029---
Respiratory arrest22.02.01.0090.000142%-
Respiratory depression17.02.05.047; 22.02.01.010---
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