Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tolazamide
Drug ID BADD_D02238
Description A sulphonylurea hypoglycemic agent with actions and uses similar to those of chlorpropamide.
Indications and Usage For use as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone.
Marketing Status approved; investigational
ATC Code A10BB05
DrugBank ID DB00839
KEGG ID D00379
MeSH ID D014042
PubChem ID 5503
TTD Drug ID D09FJB
NDC Product Code Not Available
UNII 9LT1BRO48Q
Synonyms Tolazamide | Tolinase
Chemical Information
Molecular Formula C14H21N3O3S
CAS Registry Number 1156-19-0
SMILES CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN2CCCCCC2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Agranulocytosis01.02.03.001---
Alcohol intolerance14.02.01.001--
Aplastic anaemia01.03.03.002---
Asthenia08.01.01.001---
Discomfort08.01.08.003---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Dyspepsia07.01.02.001--
Erythema23.03.06.001---
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014---
Gastrointestinal disorder07.11.01.001---
Haemolytic anaemia01.06.03.002---
Headache17.14.01.001--
Hypoglycaemia05.06.03.001; 14.06.03.001--
Hyponatraemia14.05.04.002--
Jaundice cholestatic09.01.01.005---
Leukopenia01.02.02.001---
Malaise08.01.01.003--
Nausea07.01.07.001--
Pancytopenia01.03.03.003---
Photosensitivity reaction23.03.09.003--
Porphyria non-acute03.08.01.004; 09.01.10.003; 14.14.01.004; 23.03.01.012---
Pruritus23.03.12.001--
Rash23.03.13.001---
Rash maculo-papular23.03.13.004--
Rash morbilliform23.03.13.005---
Thrombocytopenia01.08.01.002---
Urticaria10.01.06.001; 23.04.02.001--
Vertigo04.04.01.003; 17.02.12.002--
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ADReCS-Target
Drug Name ADR Term Target
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