Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Technetium tc-99m medronate
Drug ID BADD_D02129
Description Technetium (99mTc) medronic acid is a pharmaceutical product used in nuclear medicine imaging. It is composed of a technetium ion complexed with medronic acid, a type of bisphosphonate. Like other bisphosphonates used in the treatment of osteoporosis, medronic acid binds to the hydroxyapatite crystals within bone, and in this way localizes the drug to bone for delineation of areas of altered osteogenesis. Following intravenous injection, single photon emission computed tomography (SPECT) is performed to detect the gamma ray emmitted by the decay of Technetium-99m to Technetium-99.
Indications and Usage Technetium Tc 99m Medronate is indicated for use as a bone imaging agent to delineate areas of altered osteogenesis.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB09138
KEGG ID Not Available
MeSH ID D013669
PubChem ID 9838324
TTD Drug ID D0B4KH
NDC Product Code Not Available
UNII X89XV46R07
Synonyms Technetium Tc 99m Medronate | Tc-99 Medronate | Medronate, Tc-99 | Tc 99 Medronate | Technetium Methylene Diphosphonate | Diphosphonate, Technetium Methylene | Methylene Diphosphonate, Technetium | Technetium Tc 99m Methylenediphosphonate | 99mTc-Methylene Diphosphonate | 99mTc Methylene Diphosphonate | Diphosphonate, 99mTc-Methylene | 99mTc-MDP | Tc-99m MDP | Tc-99m Methylene Diphosphonate | Diphosphonate, Tc-99m Methylene | Methylene Diphosphonate, Tc-99m | Tc 99m Methylene Diphosphonate
Chemical Information
Molecular Formula CH2O6P2Tc
CAS Registry Number 121524-79-6
SMILES C(P(=O)([O-])[O-])P(=O)([O-])[O-].[Tc+4]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Arrhythmia02.03.02.001---
Asthenia08.01.01.001---
Cardiac arrest02.03.04.001--
Chills08.01.09.001; 15.05.03.016--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Hypersensitivity10.01.03.003--
Hypotension24.06.03.002--
Nausea07.01.07.001--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Vomiting07.01.07.003--
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