Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Styrenesulfonic acid
Drug ID BADD_D02077
Description Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Indications and Usage Used to treat abnormally high potassium levels.
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB01344
KEGG ID Not Available
MeSH ID C077114
PubChem ID 168625
TTD Drug ID D03RLP
NDC Product Code Not Available
UNII UHW48O2R88
Synonyms styrenesulfonic acid polymer | P-styrenesulfonic acid homopolymer | tolevamer | poly(4-styrenesulfonic acid) | poly(P-styrenesulfonic acid) | P-styrenesulfonic acid polymer | poly(sodium-4-styrenesulfonate) | poly(sodium-4-styrene sulfonate) | polysodium 4-styrenesulfonate | GT160-246
Chemical Information
Molecular Formula C8H8O3S
CAS Registry Number 26914-43-2
SMILES C=CC1=CC=CC=C1S(=O)(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bronchitis11.01.09.001; 22.07.01.001--
Colitis ischaemic07.08.01.004; 24.04.08.012---
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Drug interaction08.06.03.001---
Gastrointestinal necrosis07.15.01.003; 24.04.08.006--
Hypercalcaemia05.04.01.002; 14.04.01.003--
Hypernatraemia14.05.04.001--
Hypocalcaemia14.04.01.004--
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.001--
Intestinal obstruction07.13.01.002---
Intestinal perforation07.04.06.002---
Nausea07.01.07.001--
Necrosis08.03.03.001; 24.04.02.006---
Pneumonia11.01.09.003; 22.07.01.003---
Tracheobronchitis11.01.09.020; 22.07.01.016---
Ulcer08.03.06.001---
Vomiting07.01.07.003--
Epigastric discomfort07.01.02.004---
Faecaloma07.01.03.004---
Faecalith07.01.03.007---
Decreased appetite08.01.09.028; 14.03.01.005--
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