Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sevelamer
Drug ID BADD_D02012
Description Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Indications and Usage For the control of serum phosphorus in patients with Chronic Kidney Disease (CKD) on hemodialysis.
Marketing Status approved
ATC Code V03AE02
DrugBank ID DB00658
KEGG ID D08512
MeSH ID D000069603
PubChem ID 3085017
TTD Drug ID D03MZQ
NDC Product Code Not Available
UNII 941N5DUU5C
Synonyms Sevelamer | GT335-012 | GT335 012 | GT335012 | Sevelamer Hydrochloride | Hydrochloride, Sevelamer | RenaGel | Sevelamer Carbonate | Carbonate, Sevelamer
Chemical Information
Molecular Formula C6H12ClNO
CAS Registry Number 52757-95-6
SMILES C=CCN.C1C(O1)CCl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Constipation07.02.02.001--
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Diverticulitis07.10.02.001; 11.01.07.003---
Dyspepsia07.01.02.001--
Fatigue08.01.01.002--
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001---
Gastrointestinal pain07.01.05.005--
Hypersensitivity10.01.03.003--
Ileus07.13.01.001--
Intestinal obstruction07.13.01.002---
Intestinal perforation07.04.06.002---
Nausea07.01.07.001--
Pain08.01.08.004--
Peritonitis07.19.05.004; 11.01.07.007--
Pruritus23.03.12.001--
Rash23.03.13.001---
Vomiting07.01.07.003--
Subileus07.13.01.004---
Musculoskeletal discomfort15.03.04.001---
Faecaloma07.01.03.004---
Faecalith07.01.03.007---
Decreased appetite08.01.09.028; 14.03.01.005--
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