Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Semaxanib
Drug ID BADD_D02007
Description Not Available
Indications and Usage Investigated for use/treatment in colorectal cancer and lung cancer.
Marketing Status investigational
ATC Code Not Available
DrugBank ID DB06436
KEGG ID D05819
MeSH ID C116890
PubChem ID 5329098
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 71IA9S35AJ
Synonyms Semaxinib | SU 5416 | SU5416 | Sugen 5416 | SU-5416 | 3-(2,4-dimethylpyrrol-5-yl)methylidene-indolin-2-one
Chemical Information
Molecular Formula C15H14N2O
CAS Registry Number 194413-58-6
SMILES CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypoaesthesia17.02.06.023; 23.03.03.081---
Hypogeusia07.14.03.002; 17.02.07.004---
Hypotension24.06.03.002--
Immune system disorder10.02.01.001---
Infection11.01.08.002---
Influenza11.05.03.001; 22.07.02.001---
Influenza like illness08.01.03.010--
Injection site haemorrhage08.02.03.005; 12.07.03.005; 24.07.01.010---
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Irritability08.01.03.011; 19.04.02.013--
Lacrimation increased06.08.02.004--
Leukocytosis01.02.01.002--
Localised infection11.01.08.006---
Malaise08.01.01.003--
Migraine17.14.02.001; 24.03.05.003---
Mouth haemorrhage07.05.02.001; 24.07.02.014--
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.005---
Muscular weakness15.05.06.001; 17.05.03.005--
Musculoskeletal pain15.03.04.007--
Myalgia15.05.02.001--
Myelodysplastic syndrome01.10.04.001; 16.01.04.001--
Myelofibrosis01.13.03.005; 16.21.03.001---
Myeloid metaplasia01.13.03.004; 16.21.03.005---
Myocardial infarction02.02.02.007; 24.04.04.009--
Nasal congestion22.04.04.001--
Nasopharyngitis11.01.13.002; 22.07.03.002---
Nausea07.01.07.001--
Neoplasm16.16.02.001---
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