Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status approved
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 33342-088; 71335-1352; 62938-0020; 65977-0067; 33342-087; 63850-7138; 63850-7119
UNII 51086HBW8G
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vision blurred06.02.06.007; 17.17.01.0100.000368%
Visual impairment06.02.10.0130.000696%-
Vomiting07.01.07.0030.003273%
Wheezing22.03.01.009--
Yawning22.12.03.037---
Coronary artery dissection02.02.01.004; 12.02.01.035; 24.02.02.0010.000205%-
Hypoacusis04.02.01.006--
Acute coronary syndrome02.02.02.015; 24.04.04.011---
Eye pruritus06.04.05.006---
Musculoskeletal stiffness15.03.05.0270.000205%-
Musculoskeletal discomfort15.03.04.001---
Temperature intolerance08.01.09.022---
Urine output increased13.13.03.002---
Hot flush08.01.03.027; 21.02.02.001; 24.03.01.005--
Adverse event08.06.01.0100.000668%-
Ischaemia24.04.02.004---
Ischaemic stroke17.08.01.018; 24.04.06.0100.000136%-
Mental disorder19.07.01.002---
Cardiac valve disease02.07.02.0010.000273%-
Decreased appetite08.01.09.028; 14.03.01.005--
Inner ear disorder04.04.02.002---
Adverse drug reaction08.06.01.0090.000464%-
Drug intolerance08.06.01.0130.000696%-
Sinus disorder22.04.06.002--
Pulmonary arterial hypertension22.06.01.002; 24.08.03.0030.000341%-
Treatment failure08.06.01.0170.000764%-
Regurgitation07.01.07.004---
Drug-induced liver injury09.01.07.023; 12.03.01.0440.000136%-
Medication overuse headache08.06.02.015; 17.14.01.015---
Reversible cerebral vasoconstriction syndrome17.08.02.014; 18.06.01.004; 24.04.06.0260.000477%-
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