Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rimexolone
Drug ID BADD_D01946
Description Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Indications and Usage For the treatment of postoperative inflammation following ocular surgery and in the treatment of anterior uveitis.
Marketing Status approved
ATC Code H02AB12; S01BA13
DrugBank ID DB00896
KEGG ID D05729
MeSH ID C013769
PubChem ID 5311412
TTD Drug ID D0D2TN
NDC Product Code 60870-0423
UNII O7M2E4264D
Synonyms rimexolone | 11 beta-hydroxy-16 alpha,17 alpha,21-trimethylpregna-1,4-diene-3,20-dione | Rimexel | Vexol | Org 6216 | Org-6216
Chemical Information
Molecular Formula C24H34O3
CAS Registry Number 49697-38-3
SMILES CCC(=O)C1(C(CC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cataract subcapsular06.06.01.002---
Conjunctival oedema06.04.01.001---
Corneal erosion06.06.03.003---
Corneal oedema06.04.02.001---
Discomfort08.01.08.003---
Dry eye06.08.02.001--
Dysgeusia07.14.03.001; 17.02.07.003--
Eye discharge06.04.05.001---
Eye infection06.04.05.007; 11.01.06.001--
Eye pain06.08.03.002--
Fibrin increased13.01.02.026---
Headache17.14.01.001--
Herpes simplex11.05.02.001; 23.11.05.004---
Hyperaemia24.03.02.002---
Hypotension24.06.03.002--
Intraocular pressure increased13.07.04.002---
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Migraine17.14.02.001; 24.03.05.003---
Oedema08.01.07.006; 14.05.06.010---
Optic nerve injury06.11.02.001; 12.01.16.001; 17.04.05.008---
Pharyngitis07.05.07.004; 11.01.13.003; 22.07.03.004--
Photophobia06.01.01.004; 17.17.02.006--
Pruritus23.03.12.001--
Rhinitis11.01.13.004; 22.07.03.006--
Scab23.03.03.004---
Skin irritation23.03.04.009---
Vision blurred06.02.06.007; 17.17.01.010--
Visual acuity reduced06.02.10.012; 17.17.01.011--
Visual field defect06.02.07.003; 17.17.01.001---
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