Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Regadenoson
Drug ID BADD_D01921
Description Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Indications and Usage Diagnostic agent for radionuclide myocardial perfusion imaging (MPI)
Marketing Status approved; investigational
ATC Code C01EB21
DrugBank ID DB06213
KEGG ID D05711
MeSH ID C430916
PubChem ID 219024
TTD Drug ID D0XE1C
NDC Product Code 55150-443; 0409-1401; 76329-3321; 42973-229; 76055-0024; 60505-6116; 72611-874; 59285-029; 69766-103; 68083-175; 16729-477; 71288-201; 0641-6253; 65129-1331; 43598-616; 0469-6501; 62147-0220; 36000-364
UNII 2XLN4Y044H
Synonyms regadenoson | Lexiscan | CVT 3146 | CVT3146 | CVT-3146
Chemical Information
Molecular Formula C15H18N8O5
CAS Registry Number 313348-27-5
SMILES CNC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cardiac arrest02.03.04.0010.001395%
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.000254%-
Cerebrovascular accident17.08.01.007; 24.03.05.0010.000803%
Cerebrovascular disorder17.08.02.002; 24.03.05.002---
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.0020.002267%-
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.0030.002782%-
Chills08.01.09.001; 15.05.03.0160.000787%
Chronic obstructive pulmonary disease22.03.01.007---
Cold sweat08.01.03.024; 23.02.03.0020.000330%-
Coronary artery disease02.02.01.001; 24.04.04.0060.000127%-
Cough22.02.03.001--
Crying08.01.03.005; 12.02.11.001; 17.02.05.013; 19.04.02.0020.000288%-
Depressed level of consciousness17.02.04.0020.000372%
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.000846%-
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.0070.004136%
Dysgeusia07.14.03.001; 17.02.07.003--
Dyskinesia17.01.02.0060.000186%
Dyspnoea02.11.05.003; 22.02.01.0040.008297%
Ear disorder04.03.01.001---
Electrocardiogram QT prolonged13.14.05.004--
Electrocardiogram ST segment13.14.05.035---
Electrocardiogram ST segment depression13.14.05.005---
Erythema23.03.06.0010.001522%-
Extrasystoles02.03.02.003---
Extravasation08.01.03.0080.005320%-
Eye disorder06.08.03.001---
Eye pain06.08.03.002--
Eye swelling06.08.03.0030.000228%-
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