| Drug Name |
Promethazine |
| Drug ID |
BADD_D01854 |
| Description |
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946.[A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29 March 1951.[A190177,L4000] |
| Indications and Usage |
Promethazine tablets and suppositories are indicated to treat rhinitis, allergic conjunctivitis, allergic reactions to blood or plasma, dermographism, anaphylactic reactions, sedation, nausea, vomiting, pain, motion sickness, and allergic skin reactions.[A189907,L4000] Promethazine cough syrup with phenylephrine and codeine is indicated to relieve cough and upper respiratory symptoms, and nasal congestion associated with allergy or the common cold.[L11326] |
| Marketing Status |
approved; investigational |
| ATC Code |
D04AA10; R06AD02 |
| DrugBank ID |
DB01069
|
| KEGG ID |
D00494
|
| MeSH ID |
D011398
|
| PubChem ID |
4927
|
| TTD Drug ID |
D0T2XU
|
| NDC Product Code |
54348-117; 65162-678 |
| UNII |
FF28EJQ494
|
| Synonyms |
Promethazine | Prometazin | Proazamine | Rumergan | Diprazin | Isopromethazine | Phenergan | Phenargan | Phensedyl | Pipolfen | Pipolphen | Promet | Promethazine Hydrochloride | Hydrochloride, Promethazine | Prothazin | Pyrethia | Remsed | Atosil | Diphergan |
