Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Prilocaine
Drug ID BADD_D01836
Description A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Indications and Usage Used as a local anaesthetic and is often used in dentistry.
Marketing Status approved
ATC Code N01BB04
DrugBank ID DB00750
KEGG ID D00553
MeSH ID D011318
PubChem ID 4906
TTD Drug ID D06LYG
NDC Product Code 59014-0052; 73309-214; 24196-186; 53335-0004; 69617-011; 17381-017; 52119-020; 22365-119; 49452-6011; 82891-020
UNII 046O35D44R
Synonyms Prilocaine | Propitocaine | Citanest Octapressin | Xylonest | Citanest | Prilocaine Hydrochloride
Chemical Information
Molecular Formula C13H20N2O
CAS Registry Number 721-50-6
SMILES CCCNC(C)C(=O)NC1=CC=CC=C1C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertension24.08.02.001--
Hypoaesthesia17.02.06.023; 23.03.03.081---
Hypotension24.06.03.002--
Hypoxia22.02.02.003--
Injury12.01.08.004---
Loss of consciousness17.02.04.004---
Muscle twitching15.05.03.005---
Nausea07.01.07.001--
Nervous system disorder17.02.10.001---
Nervousness19.06.02.003---
Neuropathy peripheral17.09.03.003---
Neurotoxicity12.03.01.011; 17.02.10.002---
Oedema08.01.07.006; 14.05.06.010---
Osteoarthritis15.01.04.001---
Oxygen saturation decreased13.02.01.004---
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Paralysis17.01.04.004---
Respiratory arrest22.02.01.009---
Respiratory depression17.02.05.047; 22.02.01.010---
Respiratory failure14.01.04.003; 22.02.06.002--
Sensory loss17.02.07.007---
Shock24.06.02.002---
Somnolence17.02.04.006; 19.02.05.003--
Swelling08.01.03.015---
Syncope02.11.04.015; 17.02.04.008; 24.06.02.012--
Tension19.06.02.005---
Tinnitus04.04.01.002; 17.04.07.004--
Tremor17.01.06.002--
Urticaria10.01.06.001; 23.04.02.001--
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