Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Permethrin
Drug ID BADD_D01742
Description A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Indications and Usage For the treatment of infestation with Sarcoptes scabiei (scabies).
Marketing Status approved; investigational
ATC Code P03AC04
DrugBank ID DB04930
KEGG ID D05443
MeSH ID D026023
PubChem ID 40326
TTD Drug ID D0K8MP
NDC Product Code 36800-629; 50090-3149; 63736-035; 49348-150; 16714-897; 62011-0255; 53002-9570; 58175-0604; 11822-0549; 70000-0041; 46122-108; 59779-769; 63471-3020; 63736-030; 13746-110; 0363-0955; 55359-535; 63471-3006; 63471-3010; 0472-0242; 0113-1910; 45802-269
UNII 509F88P9SZ
Synonyms Permethrin | 3-Phenoxybenzyl-cis,trans-(1RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate | (m-Phenoxybenzyl)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate | 3-Phenoxybenzyl-(+-)-cis,trans-2,2-dichlorovinyl-2,2-dimethyl-cyclopropylcarboxylic acid, ester | Cyclopropanecarboxylic Acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester | Permethrin, (trans-(+-))-Isomer | trans-(1RS)-Permethrin | Permethrin, trans-(1RS)-Isomer | Permethrin, (trans)-Isomer | trans-permethrin | trans permethrin | S-3151 | S 3151 | S3151 | Ambush | Elimite | FMC-33297 | FMC 33297 | FMC33297 | Nittifor | NRDC-143 | NRDC 143 | NRDC143 | NRDC-147 | NRDC 147 | NRDC147 | Permethrin, (1R-cis)-Isomer | Permethrin, (1R-trans)-Isomer | Permethrin, (1S-cis)-Isomer | Permethrin, (1S-trans)-Isomer | Permethrin, (cis)-Isomer | cis-permethrin | cis permethrin | NIA-33297 | NIA 33297 | NIA33297 | Permethrin, (cis-(+-))-Isomer | permethrin, cis-(1RS)-isomer | cis-(1RS)-permethrin | PP-557 | PP 557 | PP557
Chemical Information
Molecular Formula C21Cl2H20O3
CAS Registry Number 52645-53-1
SMILES CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Body temperature increased13.15.01.001---
Burning sensation08.01.09.029; 17.02.06.001---
Dermatitis23.03.04.002---
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Erythema23.03.06.001---
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hypoaesthesia17.02.06.023; 23.03.03.081---
Nausea07.01.07.001--
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001---
Seizure17.12.03.001--
Sensory loss17.02.07.007---
Vomiting07.01.07.003--
Infestation11.09.01.001; 23.11.01.002---
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