Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Natamycin
Drug ID BADD_D01538
Description Amphoteric macrolide antifungal antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. [PubChem]
Indications and Usage For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.
Marketing Status approved
ATC Code A01AB10; A07AA03; D01AA02; G01AA02; S01AA10
DrugBank ID DB00826
KEGG ID D00884
MeSH ID D010866
PubChem ID 5284447
TTD Drug ID D02FEM
NDC Product Code 73309-346; 71776-005
UNII 8O0C852CPO
Synonyms Natamycin | Tennecetin | Pimaricin | Pimafucin | Myprozine
Chemical Information
Molecular Formula C33H47O13N
CAS Registry Number 7681-93-8
SMILES CC1CC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC3C(O3)C=CC(=O)O1)O)O)O)C(=O)O)OC4C(C(C(C(O4 )C)O)N)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Chest pain02.02.02.011; 08.01.08.002; 22.12.02.003---
Corneal opacity06.06.03.005---
Dyspnoea02.11.05.003; 22.02.01.004--
Eye irritation06.04.05.003---
Eye pain06.08.03.002--
Hyperaemia24.03.02.002---
Hypersensitivity10.01.03.003--
Lacrimation increased06.08.02.004--
Ocular hyperaemia06.04.05.004---
Paraesthesia17.02.06.005; 23.03.03.094--
Visual impairment06.02.10.013---
Eye oedema06.08.03.013---
Ocular discomfort06.08.03.008---
Sensation of foreign body08.01.09.002---
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