ADReCS

Pharmaceutical Information

Drug Name	Mometasone
Drug ID	BADD_D01490
Description	Mometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Indications and Usage	The inhaler is indicated for the maintenance treatment of asthma as prophylactic therapy. The nasal spray is indicated for the treatment of the nasal symptoms of seasonal allergic and perennial allergic rhinitis.
Marketing Status	experimental
ATC Code	D07AC13; D07XC03; R01AD09; R03BA07
DrugBank ID	DB00764
KEGG ID	D08227
MeSH ID	D000068656
PubChem ID	441335
TTD Drug ID	D03HYX
NDC Product Code	65162-891; 69238-2446
UNII	8HR4QJ6DW8
Synonyms	Mometasone Furoate \| Furoate, Mometasone \| Nasonex \| Mometasone Furoate Monohydrate \| Furoate Monohydrate, Mometasone \| Monohydrate, Mometasone Furoate \| Asmanex Twisthaler \| Twisthaler, Asmanex \| Asmanex \| Rinelon \| Elocon \| Sch 32088 \| Sch-32088 \| Sch32088 \| Mometasone

Chemical Information

Molecular Formula	C22H28Cl2O4
CAS Registry Number	105102-22-5
SMILES	CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)Cl)C
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Abdominal pain	07.01.05.002	-	-
Ageusia	07.14.03.003; 17.02.07.001	0.000231%		-
Anaphylactic reaction	10.01.07.001; 24.06.03.006	0.000059%
Anaphylactic shock	10.01.07.002; 24.06.02.004	0.000089%		-
Angioedema	10.01.05.009; 22.04.02.008; 23.04.01.001	-	-	-
Anosmia	17.04.04.001; 22.04.03.006	0.000481%
Anxiety	19.06.02.002	0.000653%
Aphonia	17.02.08.009; 19.19.01.002; 22.12.03.001	0.000119%
Application site pain	08.02.01.004; 12.07.01.004	0.000202%		-
Arthralgia	15.01.02.001	-	-
Asphyxia	12.01.08.011; 22.02.02.001	0.000059%		-
Asthenia	08.01.01.001	-	-	-
Asthma	10.01.03.010; 22.03.01.002	0.000202%		-
Back pain	15.03.04.005	-	-
Blindness	06.02.10.003; 17.17.01.003	0.000059%		-
Body temperature increased	13.15.01.001	-	-	-
Bronchitis	11.01.09.001; 22.07.01.001	-	-
Bronchospasm	10.01.03.012; 22.03.01.004	0.000089%
Burning sensation	08.01.09.029; 17.02.06.001	0.000303%		-
Cataract	06.06.01.001	0.000320%
Chest discomfort	02.02.02.009; 08.01.08.019; 22.12.02.002	0.000089%		-
Chest pain	02.02.02.011; 08.01.08.002; 22.12.02.003	-	-	-
Chills	08.01.09.001; 15.05.03.016	0.000148%
Colitis	07.08.01.001	-	-
Colitis ulcerative	07.08.01.005; 10.02.01.004	-	-	-
Conjunctivitis	06.04.01.002; 11.01.06.012	-	-
Cough	22.02.03.001	0.000884%
Deafness	04.02.01.001	0.000059%		-
Dermatitis	23.03.04.002	-	-	-
Dermatitis acneiform	23.02.01.004	-	-

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