Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Mivacurium chloride
Drug ID BADD_D01482
Description Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant. It binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission.
Indications and Usage For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Marketing Status approved
ATC Code M03AC10
DrugBank ID DB01226
KEGG ID D00763
MeSH ID D000077590
PubChem ID 5281080
TTD Drug ID D0OB2M
NDC Product Code 46439-8764
UNII 600ZG213C3
Synonyms Mivacurium | Mivacurium Chloride | BW B1090U | BW-B-1090U | BWB1090U | BW-B1090U | BW-B 1090U | BW B 1090U | BWB 1090U | Mivacron
Chemical Information
Molecular Formula C58H80Cl2N2O14
CAS Registry Number 106861-44-3
SMILES C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C(=C3)OC)OC)OC)OC)OC)CCCOC(=O)CCC=CCCC(=O)OCCC [N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C(=C6)OC)OC)OC)OC)OC)C.[Cl-].[Cl-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Arrhythmia02.03.02.001---
Bradycardia02.03.02.002---
Bronchospasm10.01.03.012; 22.03.01.004--
Dermatitis23.03.04.002---
Dizziness02.11.04.006; 17.02.05.003; 24.06.02.007--
Erythema23.03.06.001---
Flushing08.01.03.025; 23.06.05.003; 24.03.01.002--
Hypotension24.06.03.002--
Hypoxia22.02.02.003--
Immune system disorder10.02.01.001---
Injection site reaction08.02.03.014; 12.07.03.015--
Muscle spasms15.05.03.004--
Neuromuscular block prolonged12.02.20.008; 17.05.04.005---
Phlebitis12.02.01.002; 24.12.03.004--
Rash23.03.13.001---
Skin disorder23.03.03.007---
Tachycardia02.03.02.007---
Urticaria10.01.06.001; 23.04.02.001--
Wheezing22.03.01.009--
Angiopathy24.03.02.007---
Cardiac disorder02.11.01.003---
Mediastinal disorder22.09.03.001---
Therapeutic product effect decreased08.06.01.050---
Therapeutic product effect prolonged08.06.01.054---
The 1th Page    1    Total 1 Pages