Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Methylprednisolone sodium succinate
Drug ID BADD_D01436
Description A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Indications and Usage Adjunctive therapy for short-term administration in rheumatoid arthritis.
Marketing Status Prescription; Discontinued
ATC Code D07AA01; D10AA02; H02AB04
DrugBank ID DB14644
KEGG ID D00751
MeSH ID D008776
PubChem ID 23680530
TTD Drug ID Not Available
NDC Product Code 0009-0698; 0009-0047; 0009-0758; 63323-265; 68071-1792; 55150-263; 63323-258; 0009-0039; 55150-265; 55154-3941; 0009-0850; 50090-0271; 55154-3944; 63323-255; 71872-7061; 0143-9851; 55150-262; 0143-9850; 70518-2023; 71872-7232; 52584-039; 70518-3128; 0404-9958; 0009-0003; 55154-3939; 55154-3940; 55150-264; 0404-9957; 0009-0018; 52584-047
Synonyms Methylprednisolone Hemisuccinate | Hemisuccinate, Methylprednisolone | Methylprednisolone Succinate | Succinate, Methylprednisolone | Urbason-Soluble | UrbasonSoluble | Solu-Medrol | Solumedrol | A-MethaPred | Methylprednisolone Sodium Succinate | Sodium Succinate, Methylprednisolone | Methylprednisolone Hemisuccinate Monosodium Salt | 6 alpha-Methylprednisolone Sodium Hemisuccinate | Methylprednisolone Sodium Hemisuccinate | Sodium Hemisuccinate, Methylprednisolone
Chemical Information
Molecular Formula C26H33NaO8
CAS Registry Number 2375-03-3
SMILES CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
Chemical Structure
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abscess sterile08.01.05.008--Not Available
Acne23.02.01.001--Not Available
Alkalosis hypokalaemic14.01.02.002--Not Available
Alopecia23.02.02.001--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Angioedema10.01.05.009; 23.04.01.001--Not Available
Arrhythmia02.03.02.001--Not Available
Benign intracranial hypertension17.07.02.001--Not Available
Bradycardia02.03.02.002--Not Available
Calcinosis08.03.04.002--Not Available
Carbohydrate tolerance decreased13.02.02.003--Not Available
Cardiac arrest02.03.04.001--
Cardiac failure congestive02.05.01.002--Not Available
Cardiomegaly02.04.02.001--Not Available
Cataract subcapsular06.06.01.002--Not Available
Circulatory collapse24.06.02.001--Not Available
Cushingoid05.01.01.002; 14.11.01.006; 19.07.03.001; 24.08.02.004--
Depression19.15.01.001--
Dermatitis allergic10.01.03.014; 23.03.04.003--Not Available
Diabetes mellitus05.06.01.001; 14.06.01.001--Not Available
Dry skin23.03.03.001--
Ecchymosis01.01.03.001; 23.06.01.001; 24.07.06.002--Not Available
Erythema23.03.06.001--Not Available
Euphoric mood19.04.02.006--
Exophthalmos05.02.02.002; 06.09.04.001--Not Available
Fat embolism12.01.08.003; 24.01.01.012--Not Available
Fluid retention14.05.06.002; 20.01.02.003--Not Available
Glaucoma06.03.01.002--
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