Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methohexital sodium
Drug ID BADD_D01417
Description An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Indications and Usage Methohexital is indicated for use as an intravenous anaesthetic. It has also been commonly used to induce deep sedation.
Marketing Status approved
ATC Code N01AF01; N05CA15
DrugBank ID DB00474
KEGG ID D00712
MeSH ID D008723
PubChem ID 23690443
TTD Drug ID D0S8TD
NDC Product Code 42023-105
UNII 60200PNZ7Q
Synonyms Methohexital | Methohexitone | Brevimytal Natrium | Natrium, Brevimytal | Brietal-Sodium | Brietal Sodium | Methohexital Sodium | Sodium, Methohexital | Methohexital, Monosodium Salt | Monosodium Salt Methohexital | Brevital | Brietal
Chemical Information
Molecular Formula C14H17N2NaO3
CAS Registry Number 309-36-4
SMILES CCC#CC(C)C1(C(=O)N=C(N(C1=O)C)[O-])CC=C.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaphylactic reaction10.01.07.001; 24.06.03.006--
Anxiety19.06.02.002--
Apnoea22.02.01.001--
Bronchospasm10.01.03.012; 22.03.01.004--
Cardio-respiratory arrest02.03.04.002; 22.02.06.007---
Delirium19.13.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema23.03.06.001---
Headache17.14.01.001--
Hiccups07.01.06.009; 22.12.01.001--
Hypotension24.06.03.002--
Injection site pain08.02.03.010; 12.07.03.011---
Laryngospasm22.04.02.002--
Liver function test abnormal13.03.04.030---
Muscle twitching15.05.03.005---
Nausea07.01.07.001--
Peripheral circulatory failure24.06.02.020---
Pruritus23.03.12.001--
Psychomotor hyperactivity17.01.02.011; 19.11.02.003---
Respiratory depression17.02.05.047; 22.02.01.010---
Restlessness17.02.05.021; 19.11.02.002--
Rhinitis11.01.13.004; 22.07.03.006--
Salivary hypersecretion07.06.01.009---
Seizure17.12.03.001--
Tachycardia02.03.02.007---
Thrombophlebitis24.01.02.001---
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
Nerve injury12.01.12.002; 17.02.10.007---
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