Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Meperidine
Drug ID BADD_D01384
Description A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Indications and Usage Used to control moderate to severe pain.
Marketing Status approved
ATC Code N02AB02
DrugBank ID DB00454
KEGG ID D08343
MeSH ID D008614
PubChem ID 4058
TTD Drug ID D00UYE
NDC Product Code Not Available
UNII 9E338QE28F
Synonyms Meperidine | Pethidine | Isonipecain | Dolsin | Dolosal | Dolin | Operidine EPJ-I | Operidine EPJ I | Dolantin | Dolargan | Meperidine Hydrochloride | Lidol | Lydol | Demerol | Dolcontral
Chemical Information
Molecular Formula C15H21NO2
CAS Registry Number 57-42-1
SMILES CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Injection site erythema08.02.03.001; 12.07.03.001; 23.03.06.0150.001666%-
Injection site inflammation08.02.03.008; 12.07.03.009---
Injection site pain08.02.03.010; 12.07.03.011---
Injection site reaction08.02.03.014; 12.07.03.015--
Insomnia17.15.03.002; 19.02.01.002--
Irritability08.01.03.011; 19.04.02.013--
Laryngospasm22.04.02.002--
Lethargy08.01.01.008; 17.02.04.003; 19.04.04.004--
Libido decreased19.08.03.001; 21.03.02.005--
Loss of consciousness17.02.04.0040.002651%-
Miosis06.05.03.003; 17.02.11.002---
Mood swings19.04.03.001---
Muscle rigidity15.05.04.001; 17.05.02.005---
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.005---
Mydriasis06.05.03.004; 17.02.11.003---
Myoclonus17.02.05.008---
Myopathy15.05.05.001---
Nasal congestion22.04.04.001--
Nausea07.01.07.0010.089986%
Neurotoxicity12.03.01.011; 17.02.10.002---
Oedema08.01.07.006; 14.05.06.010---
Orthostatic hypotension17.05.01.020; 24.06.03.004---
Pallor08.01.03.032; 23.03.03.031; 24.03.04.001---
Palpitations02.11.04.012--
Paraesthesia17.02.06.005; 23.03.03.094--
Paralysis17.01.04.0040.000757%-
Paranoia19.05.01.005---
Periorbital oedema06.08.03.017; 10.01.05.010; 23.04.01.002--
Phlebitis12.02.01.002; 24.12.03.004--
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