Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Mefenamic acid
Drug ID BADD_D01368
Description A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Indications and Usage For the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
Marketing Status approved
ATC Code M01AG01
DrugBank ID DB00784
KEGG ID D00151
MeSH ID D008528
PubChem ID 4044
TTD Drug ID D05FTJ
NDC Product Code 80425-0306; 51552-1367; 58747-0601; 62250-677; 62350-0015; 49452-4398; 52935-0008; 51927-4457; 0276-0509; 38779-0669; 42571-258; 68180-185; 22365-117
UNII 367589PJ2C
Synonyms Mefenamic Acid | Acid, Mefenamic | Mefenaminic Acid | Pontal | Contraflam | Coslan | Parkemed | Ponstan Forte | Ponsyl | Dysman | Mefac | Mefacit | Nu-Mefenamic | Nu Mefenamic | Pinalgesic | PMS-Mefenamic Acid | PMS Mefenamic Acid | Ponalar | Ponalgic | Ponmel | Ponstan | Ponstel | Mefic | Apo-Mefenamic | Apo Mefenamic
Chemical Information
Molecular Formula C15H15NO2
CAS Registry Number 61-68-7
SMILES CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abnormal dreams17.15.02.001; 19.02.03.001---
Agranulocytosis01.02.03.001---
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004---
Anaphylactoid reaction10.01.07.003; 24.06.03.007---
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.001---
Angle closure glaucoma06.03.01.0010.002974%-
Ankylosing spondylitis10.04.04.004; 15.01.09.001---
Anxiety19.06.02.0020.002974%
Aplastic anaemia01.03.03.002---
Arrhythmia02.03.02.001---
Arthralgia15.01.02.001--
Asthenia08.01.01.001---
Asthma10.01.03.010; 22.03.01.002---
Back pain15.03.04.005--
Bladder pain20.02.02.001---
Bleeding time prolonged13.01.02.002---
Body temperature increased13.15.01.001---
Cardiac failure congestive02.05.01.002---
Chest discomfort02.02.02.009; 08.01.08.019; 22.12.02.002---
Chills08.01.09.001; 15.05.03.016--
Colitis07.08.01.001--
Coma17.02.09.001---
Confusional state17.02.03.005; 19.13.01.001--
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cystitis11.01.14.001; 20.03.02.002--
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